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Study of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for Relapsed B-cell ALL

for
B-cell Acute Lymphoblastic Leukemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 1 - 39

Code: NCT06863259

Phase1, Recruiting

Roginolisib (IOA-244) With Venetoclax and Rituximab for Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL)

for
Leukemia, Relapsed Leukemia, Chronic Lymphocytic Leukemia,
Location: Boston MA
Sponsor: Jennifer R. Brown, MD, PhD

Sex: All

Age: 18+

Code: NCT06644183

Phase1, Phase2, Recruiting

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for
Recurrent Mycosis Fungoides, Recurrent Sezary Syndrome,
Location: St Louis MO, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07003100

Recruiting

A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL

for
CTCL
Location: Boston MA, New Haven CT, Richmond VA, Rochester NY,
Sponsor: Prescient Therapeutics, Ltd.

Sex: All

Age: 18+

Code: NCT06854653

Phase2, Recruiting

Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

for
Chronic Lung Disease, Chronic Obstructive Pulmonary Disease,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 8 - 25

Code: NCT05025774

Recruiting

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Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

for
Malignancy, Hematologic, Neoplasms, Hematologic,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06904066

Phase1, Recruiting

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for
B Acute Lymphoblastic Leukemia
Location: Scarborough ME, Boston MA, Providence RI, Worcester MA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 46

Code: NCT06124157

Phase2, Recruiting

Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised Immunity

for
Adenovirus, Cytomegalovirus Infections,
Location: Palo Alto CA
Sponsor: Jessie L. Alexander

Sex: All

Age: 0 - 65

Code: NCT06909110

Phase1, Phase2, Recruiting

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

for
Philadelphia Chromosome Negative,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18 - 50

Code: NCT06785324

Recruiting

R-MVST Cells for Treatment of Viral Infections in Children and Young Adults

for
Epstein-Barr Virus, Cytomegalovirus Infections, Adenovirus,
Location: New York NY
Sponsor: Monica Bhatia

Sex: All

Age: 0 - 26

Code: NCT06926894

Phase1, Recruiting

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06910761

Phase2, Recruiting

Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

for
Leptomeningeal Metastasis
Location: San Antonio TX
Sponsor: Cerenome

Sex: All

Age: 18+

Code: NCT07098806

Phase1, Phase2, Recruiting

Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for
Lymphoblastic Leukemia, Cancer Survivors, Aplastic Anemia,
Location: Philadelphia PA, Memphis TN, Duarte CA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 10 - 30

Code: NCT05194397

Phase2, Recruiting

A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

for
Philadelphia-Negative ALL, Philadelphia-Positive ALL,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 17+

Code: NCT06287528

Phase1, Recruiting

The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors

for
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 39

Code: NCT04551378

Recruiting

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

for
Brain Cancer, Glioblastoma, Metastatic Cancer,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06058988

Phase2, Recruiting

CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

for
AML/MDS, B-ALL, T-ALL, BPDCN
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT04318678

Phase1, Recruiting

Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides

for
Localized Skin Lesion, Mycosis Fungoides
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03398161

Phase2, Recruiting

International Registry for Patients With Castleman Disease

for
Castleman Disease, Castleman's Disease,
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 0+

Code: NCT02817997

Recruiting

Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers

for
Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC)
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT04844528

Phase2, Recruiting