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CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALL

for
B-cell Acute Lymphoblastic Leukemia
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 0 - 30

Code: NCT06559189

Phase1, Recruiting

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for
Acute Leukemia of Ambiguous Lineage,
Location: Scarborough ME, Boston MA, Providence RI, Worcester MA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 1

Code: NCT06317662

Phase2, Recruiting

Study in Patients With Breast Cancer Leptomeningeal Metastasis

for
Leptomeningeal Metastasis of Breast Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 0+

Code: NCT06638294

Recruiting

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

for
Acute Lymphoblastic Leukemia in Remission,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03670966

Phase1, Phase2, Recruiting

The Leukemia and Lymphoma Society (LLS) National Research Registry

for
Blood Cancer
Location: Rye Brook NY
Sponsor: Lymphoma and Leukemia Society

Sex: All

Age: 21+

Code: NCT04806295

Recruiting

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Pembrolizumab Administered Via the Sofusa® DoseConnect™ in Patients With Relapsed/Refractory Cutaneous T-cell Lymphoma.

for
Mycosis Fungoides
Location: Duarte CA
Sponsor: Sorrento Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04118868

Phase1, Recruiting

Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma

for
Childhood Cancer
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 18+

Code: NCT06747910

Recruiting

A Study of PET Adapted Therapy and Non-invasive Monitoring for Previously Untreated Limited Stage Diffuse Large B Cell Lymphoma

for
DLBCL
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT03758989

Phase2, Recruiting

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

for
Relapsed Pediatric ALL, Hematopoietic Cell Transplantation,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT07257419

Phase1, Recruiting
Featured

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia (CLL)
Location: Boston MA, Hackensack NJ, Philadelphia PA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT04895436

Phase2, Recruiting
Featured

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia
Location: Providence RI, Worcester MA, New Haven CT, New York NY,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06428019

Phase3, Recruiting

Zanubrutinib and Tafasitamab in Mantle Cell Lymphoma

for
Mantle Cell Lymphoma
Location: Miami FL
Sponsor: Alvaro Alencar, MD

Sex: All

Age: 18+

Code: NCT06029309

Phase1, Phase2, Recruiting

Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym

for
Large B-cell Lymphoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06760156

Phase2, Recruiting

ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells

for
Hodgkin Lymphoma, Relapse, Refractory
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06090864

Phase1, Phase2, Recruiting

Rituximab, Vaccine Therapy, and GM-CSF in Treating Patients With Non-Hodgkin's Lymphoma

for
Lymphoma
Location: Nashville TN
Sponsor: Favrille

Sex: All

Age: 18+

Code: NCT00258336

Phase2, Recruiting

Zanubrutinib in Combination With Pola-R-CHP and High-dose Methotrexate in Patients With Secondary CNS Lymphoma

for
CNS Lymphoma
Location: Miami FL
Sponsor: Juan P. Alderuccio, MD

Sex: All

Age: 18+

Code: NCT06730542

Phase1, Recruiting

Studying TAK-243 in Patients With Advanced Cancer

for
Advanced Lymphoma, Advanced Malignant Solid Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06223542

Phase1, Recruiting

Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy

for
Diffuse Large B Cell Lymphoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05757219

Phase2, Recruiting

Collecting Stem Cells in Patients With Waldenstrom's Macroglobulinemia

for
Lymphoma
Location: New York NY
Sponsor: Herbert Irving Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT00899119

Recruiting

CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma

for
Peripheral T Cell Lymphoma
Location: Chapel Hill NC, Winston-Salem NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT04083495

Phase2, Recruiting