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Active & Responsive

tDCS: Sleep to Mood in Depression (S2M-D)

for
Major Depressive Disorder, MDD, Depression,
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 65

Code: NCT07572526

Recruiting
Active & Responsive

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

for
Major Depressive Disorder (MDD), Depression in Adults,
Location: New Haven CT, Toms River NJ, Philadelphia PA,
Sponsor: Cybin IRL Limited

Sex: All

Age: 18 - 70+

Code: NCT06793397

Phase3, Recruiting
Active & Responsive

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for
Major Depressive Disorder
Location: Worcester MA, New York NY, Philadelphia PA, Towson MD,
Sponsor: Syndeio Biosciences, Inc

Sex: All

Age: 18 - 64

Code: NCT07115329

Phase2, Recruiting
Active & Responsive

MicroRNA Correlates of Childhood Maltreatment and Suicidality

for
Major Depressive Disorder, Suicidal Ideation
Location: Huntsville AL, Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 60

Code: NCT04923685

Recruiting
Active & Responsive

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for
Major Depressive Disorder
Location: Boston MA, Worcester MA, New York NY, Philadelphia PA,
Sponsor: Definium Therapeutics US, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07592689

Phase3, Recruiting

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Active & Responsive

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for
Major Depressive Disorder
Location: Boston MA, Cromwell CT, Farmington CT, Cedarhurst NY,
Sponsor: Neurocrine Biosciences

Sex: All

Age: 18+

Code: NCT06966401

Phase3, Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Watertown MA, Worcester MA, Brooklyn NY, Cary NC,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase2, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for
Major Depressive Disorder (MDD)
Location: New York NY, Staten Island NY, Media PA, Miami FL,
Sponsor: Vanda Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT06830044

Phase3, Recruiting
Active & ResponsiveNew

The Medically Tailored Groceries and Mental Health Study

for
Depression / Major Depressive Disorder, Food Insecurity
Location: Worcester MA
Sponsor: University of Massachusetts, Worcester

Sex: All

Age: 18+

Code: NCT07779707

Recruiting
Active & ResponsiveNew

Enhancing Veteran-Clinical Collaboration in VA PRRCs

for
Schizophrenia, Schizoaffective Disorder, Delusional Disorder,
Location: Albuquerque NM
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT06898879

Recruiting
Active & Responsive

DBS for TRD With the Medtronic Percept PC

for
Major Depressive Disorder, Treatment Resistant Depression
Location: New York NY
Sponsor: Helen Mayberg, MD

Sex: All

Age: 25 - 70

Code: NCT05773755

Recruiting
Active & Responsive

Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression

for
Depression - Major Depressive Disorder
Location: Binghamton NY
Sponsor: Binghamton University

Sex: All

Age: 0+

Code: NCT06835855

Recruiting
Active & Responsive

Closed-Loop Deep Brain Stimulation for Major Depression

for
Major Depressive Disorder
Location: San Francisco CA
Sponsor: Andrew Krystal

Sex: All

Age: 22 - 70

Code: NCT04004169

Recruiting
Active & Responsive

Presynaptic Imaging in Major Depressive Episodes After COVID-19

for
Long COVID, Major Depressive Disorder, Major Depressive Episode
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 70+

Code: NCT06086366

Recruiting
Active & Responsive

Brain Imaging of Cognition Inn Schizophrenia and Depression

for
Schizophrenia / Schizoaffective Disorder,
Location: Ottawa
Sponsor: The Royal Ottawa Mental Health Centre

Sex: All

Age: 18 - 60

Code: NCT04159662

Recruiting
Active & Responsive

Neural Response to Inflammatory Challenge in Major Depressive Disorder

for
Major Depressive Disorder
Location: Tulsa OK
Sponsor: Laureate Institute for Brain Research, Inc.

Sex: All

Age: 18 - 65

Code: NCT04751331

Phase1, Phase2, Recruiting
Active & Responsive

Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk

for
Major Depressive Disorder (MDD), Suicidal Ideation
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 15 - 25

Code: NCT07025720

Recruiting
Active & Responsive

Lumateperone for Late-Life Depression

for
Treatment Resistant Depression (TRD),
Location: St Louis MO
Sponsor: Eric Lenze

Sex: All

Age: 60+

Code: NCT07623135

Phase3, Recruiting
Active & Responsive

Cognitive Strategies in Early Psychosis 2

for
Psychosis, Schizophrenia Disorder, Schizoaffective Disorder,
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 18 - 35

Code: NCT07263022

Phase3, Recruiting
Active & Responsive

Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)

for
Depression, MDD, Major Depressive Disorder,
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 24 - 65

Code: NCT07111390

Recruiting