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Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

for
Major Depressive Disorder
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70

Code: NCT05450432

Recruiting

Understanding and Treating Suicidal Ideation With Ketamine

for
Suicidal Ideation, Major Depressive Disorder (MDD)
Location: Ottawa
Sponsor: The Royal's Institute of Mental Health Research

Sex: All

Age: 18 - 65

Code: NCT06891300

Phase2, Phase3, Recruiting

Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback

for
Major Depressive Disorder
Location: Ann Arbor MI
Sponsor: University of Michigan

Sex: All

Age: 18 - 55

Code: NCT06050070

Recruiting

Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study

for
Major Depressive Disorder, Bipolar Disorder,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06897670

Recruiting

Measuring Psychomotor Response to L-DOPA Challenge As a Biomarker for Outcomes in Late-Life Depression: a Pilot Feasibility Trial

for
Major Depressive Disorder
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 60+

Code: NCT06626152

Phase2, Recruiting

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i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial

for
Major Depressive Disorder, Suicide,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 21 - 65

Code: NCT06480500

Phase2, Recruiting

Aβ Dynamics in LLMD

for
Alzheimer Disease, Major Depressive Disorder
Location: New York NY, Orangeburg NY
Sponsor: NYU Langone Health

Sex: All

Age: 60+

Code: NCT05004987

Recruiting

Cognitive Dysfunction in the Addictions Study - Project 4 (P4)

for
Major Depressive Disorder, Alcohol Use Disorder
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 59

Code: NCT06299787

Recruiting

Augmenting Mental Health Support Through a Supportive Text Messaging Program

for
Major Depressive Disorder, Generalized Anxiety Disorder,
Location: Halifax
Sponsor: Vincent Agyapong

Sex: All

Age: 16 - 65

Code: NCT05411302

Recruiting

Taking Action for College Students

for
Major Depressive Disorder, Bipolar Disorder, Schizophrenia
Location: Philadelphia PA
Sponsor: Temple University

Sex: All

Age: 18+

Code: NCT06700902

Recruiting

Biomarker-guided rTMS for Treatment Resistant Depression

for
Treatment Resistant Depression, Major Depressive Disorder
Location: New York NY, Stanford CA
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 22 - 65

Code: NCT04041479

Phase3, Recruiting

Personalized Indications for CBT and Antidepressants in Treating Depression

for
Major Depressive Disorder, Persistent Depressive Disorder
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 18+

Code: NCT02752542

Recruiting

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

for
Major Depressive Disorder
Location: Boston MA, Cromwell CT, Brooklyn NY, Staten Island NY,
Sponsor: Autobahn Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT06633016

Phase2, Recruiting

Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for
Major Depressive Disorder
Location: Boston MA, Mount Kisco NY, Maitland FL, Avon Lake OH,
Sponsor: Neurocrine Biosciences

Sex: All

Age: 18+

Code: NCT06786624

Phase3, Recruiting

Brain Insulin Resistance in Mood Disorders

for
Major Depressive Disorder, Bipolar Disorder, Anhedonia,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 60

Code: NCT03915613

Phase1, Phase2, Recruiting

Mindful Self-Compassion for Anxiety Disorders and Depression

for
Anxiety Disorders, Generalized Anxiety Disorder,
Location: Washington D.C. DC
Sponsor: Georgetown University

Sex: All

Age: 18 - 70+

Code: NCT05671419

Recruiting

Mood And Kids diEt (MAKE-It) Pilot Trial

for
Depression - Major Depressive Disorder, Adolescent
Location: Toronto
Sponsor: The Hospital for Sick Children

Sex: All

Age: 11 - 17

Code: NCT06716034

Recruiting

Maintenance rTMS for Depression (Maitr-De)

for
Major Depressive Disorder, Treatment Resistant Depression
Location: New York NY, San Diego CA
Sponsor: University of California, San Diego

Sex: All

Age: 18 - 70+

Code: NCT06938841

Recruiting

Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression

for
Cannabis Use, Major Depressive Disorder, Cognitive Impairment
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 55

Code: NCT04935619

Recruiting

University of Iowa Interventional Psychiatry Service Patient Registry

for
Treatment Resistant Depression, Major Depressive Episode,
Location: Iowa City IA
Sponsor: Mark Niciu

Sex: All

Age: 18 - 70+

Code: NCT04480918

Recruiting