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Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

for
Castrate Resistant Prostate Cancer,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: Male

Age: 18+

Code: NCT05766371

Phase2, Recruiting

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

for
Endometrial Cancer, Gastric Cancer,
Location: Commack NY, East Brunswick NJ, Columbus OH,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05489211

Phase2, Recruiting

Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan

for
Prostate Cancer,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: Male

Age: 18+

Code: NCT06099093

Recruiting

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Durham NC, Ann Arbor MI, Madison WI, Los Angeles CA,
Sponsor: Syntrix Biosystems, Inc.

Sex: Male

Age: 18+

Code: NCT06228053

Phase2, Recruiting

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC),
Location: Boston MA, Sarasota FL, Grand Rapids MI, Nashville TN,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06784193

Phase1, Recruiting

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The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)

for
Metastatic Castration-resistant Prostate Cancer
Location: New York NY, Toronto, Burnaby
Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited

Sex: Male

Age: 18+

Code: NCT06520345

Phase3, Recruiting

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer (Adenocarcinoma),
Location: Boston MA, Baltimore MD, Myrtle Beach SC, Tampa FL,
Sponsor: Acerand Therapeutics (Hong Kong) Limited

Sex: Male

Age: 18+

Code: NCT06801236

Phase1, Recruiting

Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer

for
mCRPC (Metastatic Castration-resistant Prostate Cancer),
Location: Detroit MI
Sponsor: Celcuity Inc

Sex: Male

Age: 18+

Code: NCT06190899

Phase1, Phase2, Recruiting

A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

for
Metastatic Castration-Resistant Prostate Cancer (mCRPC),
Location: Boston MA, Providence RI, New Haven CT, New York NY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT03972657

Phase1, Phase2, Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

for
Metastatic Castration-resistant Prostate Cancer (mCRPC),
Location: New Haven CT, Quebec, New Brunswick NJ, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136650

Phase3, Recruiting

Fecal Microbiota Transplant and Pembrolizumab for Men With Metastatic Castration Resistant Prostate Cancer.

for
Prostate Cancer, Prostate Cancer Metastatic
Location: Portland OR
Sponsor: Julie Graff, MD

Sex: Male

Age: 18+

Code: NCT04116775

Phase2, Recruiting

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer
Location: New Haven CT, New York NY, Philadelphia PA, Fairfax VA,
Sponsor: Amgen

Sex: Male

Age: 18+

Code: NCT04221542

Phase1, Recruiting

Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer

for
Prostatic Neoplasms, Castration-Resistant
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: Male

Age: 18+

Code: NCT05743621

Phase1, Recruiting

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male

Age: 18+

Code: NCT06059118

Phase2, Recruiting

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Male

Age: 18+

Code: NCT05168618

Phase2, Recruiting

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Baltimore MD, Madison WI, Seattle WA
Sponsor: University of Washington

Sex: Male

Age: 18+

Code: NCT04489719

Recruiting

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 18+

Code: NCT06616155

Phase1, Phase2, Recruiting

Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

for
Castration-resistant Prostate Cancer
Location: Salt Lake City UT, Duarte CA, Los Angeles CA
Sponsor: Edwin Posadas, MD

Sex: Male

Age: 18+

Code: NCT05534646

Phase2, Recruiting

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

for
Prostatic Neoplasms, Castration-Resistant
Location: Quebec, Montreal, Miami FL, Cleveland OH, Milwaukee WI,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06353386

Phase1, Phase2, Recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: Male

Age: 18+

Code: NCT06236139

Phase1, Phase2, Recruiting