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A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

for
ER+, HER 2- Breast Cancer, Non-small Cell Lung Cancer (NSCLC),
Location: Lake Success NY, East Brunswick NJ, Fairfax VA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18 - 70+

Code: NCT07540572

Phase1, Recruiting

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

for
Renal Cell Carcinoma, Urothelial Carcinoma,
Location: Boston MA, Philadelphia PA, Cleveland OH, Ann Arbor MI,
Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All

Age: 18+

Code: NCT06966024

Phase1, Recruiting

SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy

for
Metastatic Castration-Resistant Prostate Carcinoma
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 18+

Code: NCT07096999

Recruiting

Imaging of Solid Tumors Using 18F-TRX

for
Solid Tumor, Solid Carcinoma,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT06942104

Phase1, Recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

for
Hormone-refractory Prostate Cancer
Location: Fairfax VA, Houston TX, Seattle WA, Orange CA,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male

Age: 18+

Code: NCT05997615

Phase1, Recruiting

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Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

for
Castration-Resistant Prostate Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04693377

Recruiting

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

for
Castration-Resistant Prostate Carcinoma,
Location: South Weymouth MA, Foxborough MA, Methuen MA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06632977

Phase2, Recruiting

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

for
Metastatic Castration-resistant Prostate Neoplasms,
Location: Mineola NY, Brooklyn NY, New York NY, Philadelphia PA,
Sponsor: Janssen Research & Development, LLC

Sex: Male

Age: 18+

Code: NCT05818683

Phase1, Recruiting

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

for
Prostate Cancer, Prostate Adenocarcinoma,
Location: New York NY, Durham NC, Madison WI
Sponsor: Duke University

Sex: Male

Age: 18+

Code: NCT06141993

Recruiting

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

for
Castration-Resistant Prostate Carcinoma,
Location: Millville DE, Lewes DE, Rehoboth Beach DE,
Sponsor: SWOG Cancer Research Network

Sex: Male

Age: 18+

Code: NCT06470243

Phase3, Recruiting

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

for
Recurrent Castration-Sensitive Prostate Carcinoma,
Location: Jacksonville FL, Rochester MN, Phoenix AZ
Sponsor: Mayo Clinic

Sex: Male

Age: 18+

Code: NCT06378866

Phase2, Recruiting

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

for
Prostatic Neoplasms, Castration-Resistant
Location: New York NY, Grand Rapids MI, River Ridge LA,
Sponsor: Clarity Pharmaceuticals Ltd

Sex: Male

Age: 18+

Code: NCT04868604

Phase1, Phase2, Recruiting

A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer

for
Cancer Of Prostate, Prostate Neoplasms
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: Male

Age: 18 - 70+

Code: NCT04633252

Phase1, Phase2, Recruiting

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

for
Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant,
Location: Los Angeles CA
Sponsor: VA Greater Los Angeles Healthcare System

Sex: Male

Age: 18+

Code: NCT06706921

Recruiting

Use of SPECT-CT for Comparison of Dosimetry Methods in PSMA-targeted Radioligand Therapy (SPECTacular Study)

for
Metastatic Castration-resistant Prostate Cancer
Location: Grand Rapids MI
Sponsor: BAMF Health

Sex: Male

Age: 18+

Code: NCT05823402

Recruiting

Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC

for
Metastatic Castration-resistant Prostate Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Male

Age: 18+

Code: NCT06193486

Phase1, Recruiting

A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Lake Success NY, New York NY, Miami FL, Pittsburgh PA,
Sponsor: Syncromune, Inc.

Sex: Male

Age: 18+

Code: NCT06533644

Phase2, Recruiting

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

for
Advanced Solid Tumor, Diffuse Large B Cell Lymphoma,
Location: Boston MA, Philadelphia PA, Charlottesville VA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT04104776

Phase1, Phase2, Recruiting

A Clinical Trial Evaluating the Safety of TD001 In Patients With PSMA-Expressing Metastatic Prostate Cancer

for
Metastatic Castration-Resistant Prostatic Cancer
Location: Toronto
Sponsor: T.O.A.D. Oncology SA

Sex: Male

Age: 18+

Code: NCT07258407

Phase1, Phase2, Recruiting

Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC

for
Metastatic Castration-resistant Prostate Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Male

Age: 18+

Code: NCT07476001

Phase2, Recruiting