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Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07214298

Phase1, Phase2, Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for
Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma
Location: Chicoutimi, New York NY, Summit NJ, New Brunswick NJ,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06989437

Phase2, Phase3, Recruiting

ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06904378

Phase1, Phase2, Recruiting

Prospectively Defining Metastatic Pancreatic Ductal Adenocarcinoma Subtypes by Comprehensive Genomic Analysis

for
Cancer, Pancreatic Cancer
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT02869802

Recruiting

Endoscopic Ultrasound Radiofrequency Ablation and Immunotherapy Pembrolizumab for Locally Advanced Unresectable and Metastatic Pancreatic Duct Adenocarcinoma

for
Pancreatic Ductal Adenocarcinoma
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT06831136

Phase2, Recruiting

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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for
Solid Tumors
Location: Boston MA, Lake Success NY, The Bronx NY, New York NY,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT07522073

Phase3, Recruiting

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Ductal Adenocarcinoma (PDAC)
Location: New York NY, Philadelphia PA, Jacksonville FL,
Sponsor: BicycleTx Limited

Sex: All

Age: 18+

Code: NCT07450859

Phase2, Recruiting

Monthly Alternating NALIRIFOX and GnP in the First-Line Setting for Metastatic Pancreatic Ductal Adenocarcinoma

for
Pancreatic Ductal Adenocarcinoma
Location: Bay Shore NY, New Hyde Park NY, Mount Kisco NY,
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT07163273

Phase2, Recruiting

CHemotherapy and Stool Transplant in PDAC (CHASe-PDAC)

for
Unresectable or Metastatic Advanced Pancreatic Ductal Adenocarcinoma,
Location: London
Sponsor: John Lenehan

Sex: All

Age: 18+

Code: NCT06393400

Phase1, Recruiting

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: Boston MA, New Haven CT, East Brunswick NJ,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07621718

Phase3, Recruiting

CT-95 in Advanced Cancers Associated With Mesothelin Expression

for
Mesothelin-Expressing Tumors, Epithelial Ovarian Cancer,
Location: Hackensack NJ, Philadelphia PA, Grand Rapids MI,
Sponsor: Context Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06756035

Phase1, Recruiting

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma,
Location: Toronto, Dallas TX, San Antonio TX
Sponsor: Auricula Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07148128

Phase1, Phase2, Recruiting

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Ductal Adenocarcinoma (PDAC)
Location: Boston MA, Worcester MA, New York NY, Philadelphia PA,
Sponsor: SOFIE

Sex: All

Age: 18+

Code: NCT07217717

Phase3, Recruiting

A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

for
Pancreatic Cancer, Metastatic,
Location: New York NY, Summit NJ, Maumee OH
Sponsor: Engeneic Pty Limited

Sex: All

Age: 18+

Code: NCT07049055

Phase1, Phase2, Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for
Cervical Cancer,
Location: Hackensack NJ, Montreal, Hamilton, Nashville TN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT04895709

Phase1, Phase2, Recruiting

Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Long Branch NJ, New York NY, Livingston NJ,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04172532

Phase1, Phase2, Recruiting

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

for
Advanced Biliary Tract Carcinoma, Advanced Colorectal Carcinoma,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT05733000

Phase2, Recruiting

Padeliporfin VTP Treatment for Unresectable Pancreatic Adenocarcinoma

for
Locally Advanced Unresectable Pancreatic Adenocarcinoma
Location: Duarte CA, Irvine CA
Sponsor: Impact Biotech Ltd

Sex: All

Age: 18+

Code: NCT05919238

Phase1, Recruiting

Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC

for
Pancreas Cancer, Metastatic Pancreatic Cancer,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04605913

Phase1, Phase2, Recruiting

Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields in Metastatic Pancreatic Cancer

for
Pancreatic Cancer, Metastatic Adenocarcinoma
Location: Winston-Salem NC
Sponsor: THERABIONIC INC.

Sex: All

Age: 18+

Code: NCT05776524

Phase2, Recruiting