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Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer,
Location: Boston MA, New York NY, Madison WI, Aurora CO,
Sponsor: I-Mab Biopharma US Limited

Sex: All

Age: 18+

Code: NCT04900818

Phase1, Recruiting

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for
Advanced Cancer, Metastatic Cancer, Ovarian Cancer,
Location: Lake Success NY, Philadelphia PA, East Syracuse NY,
Sponsor: Artios Pharma Ltd

Sex: All

Age: 18+

Code: NCT04657068

Phase1, Phase2, Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for
Solid Tumors With HRAS Alterations,
Location: Boston MA, New Brunswick NJ, Pittsburgh PA,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06026410

Phase1, Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

for
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer,
Location: Boston MA, Montreal, Toronto, Jacksonville FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06562192

Phase1, Recruiting

Using Tumour DNA and Proteins to Better Understand How Pancreatic Cancer Responds to Treatment

for
Pancreatic Ductal Adenocarcinoma,
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT06574620

Recruiting

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A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

for
Head and Neck Squamous Cell Carcinoma HNSCC,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Sutro Biopharma, Inc.

Sex: All

Age: 18+

Code: NCT07227168

Phase1, Recruiting

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma,
Location: Bath ME, Portland ME, Scarborough ME, South Portland ME,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06958328

Phase3, Recruiting

Adaptive Radiation for Locally Advanced Unresectable Pancreatic Cancer

for
Locally Advanced Pancreatic Ductal Adenocarcinoma (PDA)
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT06984562

Recruiting

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for
Non-small Cell Lung Cancer, Colorectal Carcinoma,
Location: Boston MA, New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06218914

Phase1, Recruiting

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

for
PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06922591

Phase1, Phase2, Recruiting

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

for
Vulvar Adenocarcinoma, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Fairfax VA, Grand Rapids MI, Irving TX
Sponsor: Avacta Life Sciences Ltd

Sex: All

Age: 18+

Code: NCT07454642

Phase1, Recruiting

Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

for
Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma,
Location: New Haven CT, New York NY, Rochester NY, Detroit MI,
Sponsor: Panbela Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05254171

Phase2, Phase3, Recruiting

Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors

for
Gastric Cancer, Gastro-esophageal Junction Cancer,
Location: Jacksonville FL, Rochester MN
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06005493

Phase1, Phase2, Recruiting
New

Sacituzumab Tirumotecan +/- Pembrolizumab in I/O Exposed Metastatic or Recurrent Ovarian Clear Cell Cancer

for
Ovarian Clear Cell Carcinoma, Metastatic Ovarian Cancer,
Location: Boston MA
Sponsor: Tufts Medical Center

Sex: Female

Age: 18+

Code: NCT07718854

Phase2, Recruiting

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for
Non Small Cell Lung Cancer, Lung Cancer, Breast Cancer,
Location: Boston MA, New Haven CT, New York NY,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT05983432

Phase1, Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for
Diffuse Astrocytoma, IDH-Mutant, Glioblastoma, IDH-wildtype,
Location: Boston MA, Boynton Beach FL, Nashville TN, Dallas TX,
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06047379

Phase1, Phase2, Recruiting

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

for
Early Stage Triple-Negative Breast Carcinoma,
Location: Jacksonville FL, Rochester MN, Phoenix AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06349642

Recruiting

A Study of KK2269 in Adult Participants With Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Jacksonville FL, St Louis MO, Dallas TX, Scottsdale AZ,
Sponsor: Kyowa Kirin Co., Ltd.

Sex: All

Age: 18+

Code: NCT06266299

Phase1, Recruiting

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer, Squamous Cell Carcinoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02133196

Phase2, Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

for
Metastatic Malignant Solid Neoplasm, Metastatic Melanoma,
Location: Duarte CA, Los Angeles CA, Stanford CA
Sponsor: Anusha Kalbasi

Sex: All

Age: 18 - 70+

Code: NCT04119024

Phase1, Recruiting