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REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma

for
Metastatic Castration-Resistant Prostate Cancer (mCRPC),
Location: Tampa FL, Zion IL, Houston TX, Goodyear AZ, Duarte CA
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07594106

Phase1, Phase2, Recruiting

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

for
Gastric Cancer, Gastric Adenocarcinoma,
Location: Fairfax VA
Sponsor: BigHat Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07529808

Phase1, Phase2, Recruiting

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Peabody MA, Burlington MA, Livonia MI, Canton MI,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07383441

Phase3, Recruiting

VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07510334

Phase2, Recruiting

Drug Screening Using Novel IMD in Renal Cell Carcinoma

for
Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma,
Location: Boston MA
Sponsor: Oliver Jonas

Sex: All

Age: 18+

Code: NCT05700461

Phase1, Recruiting

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Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

for
Advanced Biliary Tract Carcinoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07405086

Recruiting

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

for
Metastatic Renal Cell Carcinoma, Metastatic Renal Cancer,
Location: Boston MA
Sponsor: Stephanie Berg

Sex: All

Age: 18+

Code: NCT07123090

Phase2, Recruiting

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07128680

Phase1, Recruiting

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

for
Advanced Renal Cell Carcinoma (aRCC),
Location: Hershey PA, Washington D.C. DC, Chapel Hill NC,
Sponsor: Brian Rini

Sex: All

Age: 18+

Code: NCT07188896

Phase2, Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

for
Renal Cell Carcinoma (RCC),
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT05176483

Phase1, Recruiting

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

for
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma, RCC,
Location: New Haven CT, Lake Success NY, New York NY, Fairfax VA,
Sponsor: Neomorph, Inc

Sex: All

Age: 18+

Code: NCT07300241

Phase1, Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for
Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: Plexium, Inc.

Sex: All

Age: 18+

Code: NCT07284186

Phase1, Recruiting

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

for
Cutaneous Squamous Cell Carcinoma,
Location: Uniondale NY, New York NY, Middletown NJ, Montvale NJ,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05859074

Phase1, Recruiting

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Bath ME, Portland ME, Scarborough ME, Sanford ME,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase3, Recruiting

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for
Metastatic Clear Cell Renal Cell Carcinoma,
Location: Boston MA, New Haven CT, Sherbrooke, New York NY,
Sponsor: Arcus Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07011719

Phase3, Recruiting

Effects of Belzutifan on 89Zr-DFO-girentuximab PET Uptake in Patients With Renal Cell Carcinoma (RCC)

for
Metastatic Clear Cell Renal Cell Carcinoma
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07179770

Phase1, Recruiting

A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States

for
Advanced Unresectable Gastric Adenocarcinoma,
Location: Coral Springs FL, Tamarac FL, Plantation FL, Hialeah FL,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07554521

Phase2, Recruiting

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for
Urothelial Carcinoma Bladder,
Location: New York NY, Glen Burnie MD, Miami FL, Pittsburgh PA,
Sponsor: Aktis Oncology, Inc.

Sex: All

Age: 18+

Code: NCT07020117

Phase1, Recruiting

Imaging of Solid Tumors Using 18F-TRX

for
Solid Tumor, Solid Carcinoma,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT06942104

Phase1, Recruiting

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for
Carcinoma, Renal Cell, Advanced Renal Cell Carcinoma,
Location: Boston MA, Newton MA, Commack NY, Uniondale NY,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07227415

Phase1, Phase2, Recruiting