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A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)

for
High Risk Smoldering Multiple Myeloma (HR-SMM)
Location: Boston MA, New York NY, Columbus OH, Detroit MI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07393282

Phase3, Recruiting

Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)

for
Multiple Myeloma, Multiple Myeloma in Relapse,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07200089

Phase1, Recruiting

A Study to Compare the PK Characteristics, Safety, Tolerability, and Immunogenicity of HLX15-SC With DARZALEX FASPRO® in Combination With Lenalidomide and Dexamethasone (Rd) in Transplant-ineligible Patients With Newly Diagnosed Multiple Myeloma

for
Multiple Myeloma (MM)
Location: Tamarac FL, Plantation FL, Margate FL, Jacksonville FL,
Sponsor: Shanghai Henlius Biotech

Sex: All

Age: 18+

Code: NCT07477587

Phase1, Recruiting

Horizon Two: HR NDMM (MMRC-100)

for
High Risk Newly Diagnosed Multiple Myeloma
Location: New York NY, Chapel Hill NC, Detroit MI, Atlanta GA,
Sponsor: Multiple Myeloma Research Consortium

Sex: All

Age: 18+

Code: NCT07053436

Phase2, Recruiting

Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma

for
Relapse Multiple Myeloma, Refractory Multiple Myeloma
Location: Madison WI
Sponsor: Natalie Callander

Sex: All

Age: 18+

Code: NCT07479979

Phase1, Phase2, Recruiting

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A Phase 1 Study of Vaccination With Dendritic Cell (DC)/Multiple Myeloma (MM) Fusions in Combination With Elranatamab in Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma, Relapse Multiple Myeloma,
Location: Boston MA
Sponsor: David Avigan

Sex: All

Age: 18+

Code: NCT06799026

Phase1, Recruiting

Pre-malignant States to Hematologic Malignancies in Firefighters

for
Clonal Hematopoiesis of Indeterminate Potential,
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 40 - 49

Code: NCT06870760

Recruiting

Talquetamab & Lenalidomide as Post Stem Cell Transplant Maintenance in Multiple Myeloma

for
Multiple Myeloma, Post Stem Cell Transplant
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06461988

Phase2, Recruiting

Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma Refractory, Multiple Myeloma in Relapse
Location: Boston MA, Hackensack NJ, New Brunswick NJ,
Sponsor: CellCentric Ltd.

Sex: All

Age: 18+

Code: NCT07096778

Phase2, Recruiting

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

for
Multiple Myeloma
Location: Halifax, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT05020236

Phase3, Recruiting

A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

for
Relapsed and/or Refractory Multiple Myeloma (RRMM)
Location: New York NY, Columbus OH, Atlanta GA, Houston TX,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07222761

Phase3, Recruiting

Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response With Talquetmab and Teclistamab (ROTATE)

for
Multiple Myeloma
Location: New Haven CT
Sponsor: Noffar Bar

Sex: All

Age: 18+

Code: NCT06993675

Phase2, Recruiting

Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for
Multiple Myeloma, Newly Diagnosed, Multiple Myeloma (MM)
Location: Norfolk VA, Chapel Hill NC, Columbus OH, Birmingham AL,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 19+

Code: NCT06974786

Phase2, Recruiting

Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors

for
Cancer, Cancer Survivors, Gastrointestinal Cancers,
Location: Detroit MI
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 18+

Code: NCT06908629

Recruiting

A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments

for
Multiple Myeloma
Location: Boston MA, Wilson NC, Chapel Hill NC, Pembroke Pines FL,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT05714839

Phase1, Phase2, Recruiting

PET/MR Scan With [68Ga]Ga-PentixaFor (CXCR4) vs Standard of Care (SOC) for Initial Staging and Follow up in Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06871176

Recruiting

A Study of Dara-RVd and Teclistamab-RVd in People With Multiple Myeloma

for
Multiple Myeloma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07099391

Phase1, Phase2, Recruiting

Linvoseltamab in Addition to Lenalidomide (L2) During Maintenance Therapy of NDMM to Deepen Responses or Redrive MRD Negativity After Relapse

for
Multiple Myeloma
Location: Miami FL
Sponsor: Dickran Kazandjian, MD

Sex: All

Age: 0+

Code: NCT06910124

Phase2, Recruiting

A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for
Multiple Myeloma
Location: New York NY, Charlottesville VA, Tampa FL, Atlanta GA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07073547

Phase1, Recruiting

Integrated Cancer Repository for Cancer Research

for
Pancreatic Cancer, Thyroid Cancer, Lung Cancer,
Location: Manchester CT, Holyoke MA, Glens Falls NY, Utica NY,
Sponsor: University of Nebraska

Sex: All

Age: 19 - 70+

Code: NCT02012699

Recruiting