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Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer

for
Advanced Prostate Adenocarcinoma,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: Male

Age: 18+

Code: NCT06173362

Phase2, Recruiting

Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma

for
Melanoma, Melanoma Stage III, Melanoma (Skin),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06771544

Phase2, Recruiting

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Boston MA, Pittsburgh PA, Houston TX, Newport Beach CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT05372640

Phase1, Recruiting

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

for
Unresectable Melanoma, Metastatic Melanoma,
Location: New York NY, Miami FL, Pittsburgh PA, Orlando FL,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT05361174

Phase1, Phase2, Recruiting

Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic Cancer

for
Stage III Thymoma AJCC v8, Stage IIIA Thymoma AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03295227

Phase1, Recruiting

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Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Boston MA, Mineola NY, New York NY, Columbus OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05422794

Phase1, Recruiting

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

for
Large B-Cell Lymphoma With IRF4 Rearrangement,
Location: Jacksonville FL, La Crosse WI, Eau Claire WI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06834373

Phase2, Recruiting

Limited-duration Teclistamab

for
Myeloma Multiple
Location: New York NY, Philadelphia PA, Iowa City IA,
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT05932680

Phase2, Recruiting

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

for
Heart Failure, Heart Failure NYHA Class II,
Location: Jacksonville FL, Tampa FL, Clearwater FL,
Sponsor: CVRx, Inc.

Sex: All

Age: 18+

Code: NCT07232030

Recruiting

Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT05741164

Phase2, Recruiting

Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-III)

for
Psoriasis Vulgaris, Topical Administration, Phase III
Location: New York NY
Sponsor: Psoriasis Research Institute of Guangzhou

Sex: All

Age: 18 - 70

Code: NCT07426120

Phase3, Recruiting

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for
Advanced Hepatocellular Carcinoma,
Location: Boston MA, Waterford CT, Guilford CT, Glastonbury CT,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07166406

Phase3, Recruiting

CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer

for
FIGO Stage III and IV Ovarian Cancer, Fallopian Tube Cancers,
Location: New York NY, Durham NC, Rochester MN, Irvine CA,
Sponsor: TORL Biotherapeutics, LLC

Sex: Female

Age: 18 - 70+

Code: NCT07322094

Phase1, Phase2, Recruiting

Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma

for
Cutaneous Melanoma, Cutaneous Melanoma, Stage III,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT07148245

Recruiting

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

for
Heart Failure and Reduced Ejection Fraction,
Location: Marlton NJ
Sponsor: Impulse Dynamics

Sex: All

Age: 18+

Code: NCT07209098

Recruiting

Safety and Efficacy of ONT01 in Lupus

for
Lupus Nephritis (LN), Lupus Nephritis - WHO Class III,
Location: New York NY
Sponsor: Hospital for Special Surgery, New York

Sex: All

Age: 18+

Code: NCT07107659

Early_phase1, Recruiting

NORM-HF Pivotal Study

for
Heart Failure, NYHA Class III Heart Failure,
Location: Philadelphia PA, Jacksonville FL, Tampa FL,
Sponsor: Foundry Innovation & Research 1, Limited (FIRE1)

Sex: All

Age: 18+

Code: NCT07574593

Recruiting

HEME Home Transfusion Program

for
Leukemia, Myeloma, Myelodysplastic Syndromes,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06487247

Recruiting

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

for
Type III Achalasia,
Location: Boston MA, Charlotte NC, Gainesville FL, Cleveland OH,
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT07293689

Recruiting

Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms

for
Technical Sucess,
Location: Springfield MA
Sponsor: Baystate Medical Center

Sex: All

Age: 18+

Code: NCT07019454

Recruiting