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Duloxetine for LBP

for
Back Pain, Low
Location: The Bronx NY
Sponsor: Montefiore Medical Center

Sex: All

Age: 18 - 64

Code: NCT05851976

Recruiting

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

for
Leukemia, Acute Myeloid Leukemia in Remission, Myelodysplasia,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 0 - 25

Code: NCT05794880

Recruiting

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

for
Melanoma (Skin Cancer),
Location: Lake Success NY, Fairfax VA, Detroit MI, Cincinnati OH,
Sponsor: Aminex Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07287917

Phase1, Phase2, Recruiting

Biologic Injection For Adults With Lumbar Disc Herniation

for
Degenerative Disc Disease, DDD,
Location: Manhattan NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT07386548

Recruiting

The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity

for
Venous Thromboembolism, Postpartum Period, Aspirin,
Location: Calgary
Sponsor: University of Calgary

Sex: Female

Age: 18+

Code: NCT06494878

Phase3, Recruiting

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Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment

for
Retinitis Pigmentosa (RP), Rod Cone Dystrophy,
Location: Waterloo
Sponsor: University of Waterloo

Sex: All

Age: 18+

Code: NCT07341763

Recruiting

Brain Mechanisms Supporting Cannabis-induced Pain Relief

for
Sciatica, Lumbar Radiculopathy, Lower Back Pain,
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 21 - 65

Code: NCT04982965

Early_phase1, Recruiting

Optimization of Cardiac Imaging in Women With Early-Stage Breast Cancer

for
Breast Cancer With Low to Intermediate HER2 Expression
Location: Rochester NY
Sponsor: University of Rochester

Sex: Female

Age: 18 - 70+

Code: NCT07630402

Recruiting

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

for
PIK3CA Mutations, Advanced Solid Tumors, Adult,
Location: Boston MA, East Brunswick NJ, Fairfax VA, Tampa FL,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07383506

Phase1, Recruiting

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

for
Locally Advanced Cancer, Metastatic Cancer, HER2,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06828588

Early_phase1, Recruiting

ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer

for
Metastatic Breast Cancer, HER2 Low Breast Carcinoma,
Location: Boston MA
Sponsor: Kristina A. Fanucci

Sex: All

Age: 18+

Code: NCT07198724

Phase1, Phase2, Recruiting

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

for
Brain Cancer, Brain Tumor, Brain Neoplasms, Primary Brain Tumor,
Location: Lebanon NH
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 18+

Code: NCT06930846

Recruiting

Hormones, Outcomes, and Pain Pathways in Exercise Study

for
Breast Pain, Mastalgia, Back Pain, Back Pain, Low, Neck Pain,
Location: Houston TX
Sponsor: University of Houston

Sex: Female

Age: 18 - 60

Code: NCT07579182

Phase1, Recruiting

Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study

for
Overweight, Obesity, Hypertension, Prehypertension, Anxiety,
Location: Miami FL
Sponsor: Duke University

Sex: All

Age: 6 - 14

Code: NCT06595251

Recruiting

Neonatal Platelet Transfusion Threshold Trial

for
Thrombocytopenia, Neonatal, Platelet Transfusion,
Location: Boston MA, Philadelphia PA, Rochester NY, Durham NC,
Sponsor: NICHD Neonatal Research Network

Sex: All

Age: 0

Code: NCT06676904

Recruiting

Atlantic Lipid Lowering Treatment Optimization Program

for
Familial Hypercholesterolemia,
Location: Springfield NJ
Sponsor: Atlantic Health System

Sex: All

Age: 18 - 70+

Code: NCT06439654

Recruiting

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

for
Breast Neoplasms, Triple Negative Breast Neoplasms,
Location: St. John's, Westbrook ME, Boston MA, Quebec, Sherbrooke,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06966700

Phase3, Recruiting

Safety of MT-401-OTS in Patients With Relapsed AML or MDS

for
Acute Myeloid Leukemia, in Relapse, MDS
Location: Tampa FL, Kansas City KS, Duarte CA
Sponsor: Marker Therapeutics, Inc.

Sex: All

Age: 65+

Code: NCT06552416

Phase1, Recruiting

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

for
Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS,
Location: Baltimore MD, Washington D.C. DC
Sponsor: Catherine Bollard

Sex: All

Age: 0 - 70+

Code: NCT02203903

Phase1, Recruiting
New

Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

for
Acute Myeloid Leukemia With Complex Karyotype,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07582172

Phase2, Recruiting