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Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

for
Leukemia, Lymphoma, Multiple Myeloma,
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 19+

Code: NCT04898790

Recruiting

CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

for
Blasts 10-19 Percent of Bone Marrow Nucleated Cells,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03896269

Phase1, Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 39

Code: NCT05800210

Phase2, Recruiting

Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS)

for
Clonal Cytopenia of Undetermined Significance,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05483010

Phase2, Recruiting

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

for
Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute,
Location: Boston MA, New Brunswick NJ, Morristown NJ,
Sponsor: Sumitomo Pharma America, Inc.

Sex: All

Age: 12+

Code: NCT04988555

Phase1, Phase2, Recruiting

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Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy

for
Myelodysplastic Syndrome, Acute Myeloid Leukemia
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 0+

Code: NCT06510868

Recruiting

Red Blood Cell Transfusion Thresholds and QOL in MDS

for
Myelodysplastic Syndromes (MDS), Quality of Life,
Location: Toronto, Hamilton
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT02099669

Recruiting

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS

for
Whole Genome Sequencing, Acute Myeloid Leukemia,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT04986657

Recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

for
Hematologic Malignancy, Bone Marrow Transplant Rejection,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT06398457

Early_phase1, Recruiting

A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: New York NY, Kansas City KS, Duarte CA
Sponsor: GluBio Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06146257

Phase1, Recruiting

Study of Sapacitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: Houston TX
Sponsor: Cyclacel Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT01211457

Phase1, Phase2, Recruiting

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

for
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18 - 70+

Code: NCT01890486

Recruiting

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

for
Relapsed or Refractory Acute Myeloid Leukemia (AML),
Location: Charleston SC, Houston TX, Dallas TX
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT02074839

Phase1, Recruiting

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

for
B-Cell Non-Hodgkin Lymphoma,
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03017820

Phase1, Recruiting

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

for
Leukemia, Myeloid, Acute, Refractory AML, Relapsed Adult AML,
Location: New Haven CT, Durham NC, Miami FL, Columbus OH,
Sponsor: Aptose Biosciences Inc.

Sex: All

Age: 18+

Code: NCT03850574

Phase1, Phase2, Recruiting

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for
Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00801489

Phase2, Recruiting

A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)

for
Myelodysplastic Syndromes
Location: Tampa FL
Sponsor: Lixte Biotechnology Holdings, Inc.

Sex: All

Age: 18+

Code: NCT03886662

Phase1, Phase2, Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06195891

Phase1, Recruiting

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

for
Myeloid Malignancy, Inherited Bone Marrow Failure Syndrome,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT02958462

Recruiting

JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation

for
MYELODYSPLASTIC SYNDROME; MDS, ACUTE MYELOID LEUKEMIA; AML
Location: Chicago IL, Salt Lake City UT, Seattle WA, Portland OR,
Sponsor: Jasper Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04429191

Phase1, Recruiting