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A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for
Solid Tumor, Adult, Refractory Cancer,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: GV20 Therapeutics

Sex: All

Age: 18+

Code: NCT05669430

Phase1, Phase2, Recruiting

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

for
Cervical Cancer, Breast Cancer, Colon Cancer, NSCLC,
Location: Glen Burnie MD, Lexington KY, Omaha NE
Sponsor: Orano Med Theranostics, SAS

Sex: All

Age: 18+

Code: NCT05283330

Phase1, Recruiting

A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors

for
Neoplasms, Neoplasm Metastasis, Non-Small-Cell Lung Cancer
Location: Boston MA, Canton OH, Detroit MI
Sponsor: Shanghai EpimAb Biotherapeutics Co., Ltd.

Sex: All

Age: 18+

Code: NCT03797391

Phase1, Phase2, Recruiting

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

for
Non-small Cell Lung Cancer
Location: The Bronx NY, Salisbury MD, Baltimore MD, Pinehurst NC,
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06745882

Phase2, Recruiting

Quick Start Durvalumab Following Chemoradiation for Stage III Nonsmall Cell Lung Cancer

for
Nonsmall Cell Lung Cancer Stage III,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT05696782

Phase2, Recruiting

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A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

for
Unresectable Melanoma, Metastatic Melanoma,
Location: New York NY, Miami FL, Pittsburgh PA, Orlando FL,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT05361174

Phase1, Phase2, Recruiting

Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18F]-FARAG

for
Advanced Non Small Cell Lung Cancer
Location: Iowa City IA
Sponsor: CellSight Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06107374

Phase2, Recruiting

Effects of Selected Vegetable and Herb Mix (SV) on Advanced Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: New York NY
Sponsor: Sun Farm Corporation

Sex: All

Age: 18+

Code: NCT00246727

Phase3, Recruiting

First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies

for
Triple Negative Breast Cancer, Hormone-Resistant Breast Cancer,
Location: Baltimore MD
Sponsor: A&G Pharmaceutical Inc.

Sex: All

Age: 18+

Code: NCT05627960

Phase1, Recruiting

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

for
Solid Tumor, Advanced Cancer, Metastatic Cancer,
Location: Tampa FL
Sponsor: Memgen, Inc.

Sex: All

Age: 18+

Code: NCT05076760

Phase1, Recruiting

Repositioning Immunotherapy in VetArans With Lung Cancer

for
Non-Small Cell Lung Cancer
Location: West Haven CT, Washington D.C. DC, Richmond VA,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT06275360

Phase2, Recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for
Metastatic Non-small Cell Lung Cancer
Location: Boston MA, Quebec, The Bronx NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06417814

Phase3, Recruiting

A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for
NSCLC (Advanced Non-small Cell Lung Cancer)
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: BlossomHill Therapeutics

Sex: All

Age: 18+

Code: NCT06706076

Phase1, Phase2, Recruiting

Ladarixin With Sotorasib in Advanced NSCLC

for
Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation
Location: Garden City NY, Mineola NY, New Hyde Park NY,
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 70+

Code: NCT05815173

Phase1, Recruiting

Molecularly Targeted Radionuclide Therapy Via the Integrin Alphavbeta6

for
Metastatic Nonsmall Cell Lung Cancer
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06228482

Phase1, Recruiting

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for
Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer,
Location: Boston MA, Commack NY, Baltimore MD, Ottawa, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05123482

Phase1, Phase2, Recruiting

Using ctDNA to Detect Minimal Residual Disease After Lung Cancer Resection

for
Non Small Cell Lung Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05254782

Recruiting

Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer with Osimertinib Third-line Rechallenge

for
Non-Small Cell Lung Cancer
Location: Ottawa, Oshawa, Toronto, Brampton, Hamilton, Kitchener,
Sponsor: Mark Vincent

Sex: All

Age: 18+

Code: NCT04335292

Phase2, Recruiting

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for
Non-small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Mineola NY, Harrison NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06077760

Phase3, Recruiting

Study of XB010 in Subjects With Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors,
Location: The Bronx NY, Washington D.C. DC, Fairfax VA,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT06545331

Phase1, Recruiting