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LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)

for
Non-small Cell Lung Cancer, Oligoprogressive,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06103682

Recruiting

Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer

for
Non-small Cell Lung Cancer
Location: Waterford CT, Guilford CT, Hamden CT, New Haven CT,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT04210492

Phase1, Phase2, Recruiting

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

for
Advanced or Metastatic Non-small Cell Lung Cancer
Location: Providence RI, Baltimore MD, Jacksonville FL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06996782

Phase1, Phase2, Recruiting

A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Farmington Hills MI, Atlanta GA, Farmington NM, Reno NV,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07541170

Phase3, Recruiting

Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Cardiotoxicity,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07761910

Phase2, Recruiting

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Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for
Solid Tumor, Non-Small Cell Lung Cancer, Head and Neck Cancer,
Location: Orange City FL, Clermont FL, Detroit MI, Atlanta GA,
Sponsor: Inhibrx Biosciences, Inc

Sex: All

Age: 18+

Code: NCT04198766

Phase1, Phase2, Recruiting

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Lake Success NY, Buffalo NY, Sarasota FL,
Sponsor: InduPro, Inc.

Sex: All

Age: 18+

Code: NCT07602842

Phase1, Phase2, Recruiting

Precise Exercise Regimen for Cancer Care (PERCC): A Pilot Study

for
Stage II Lung Cancer, Lung Cancer, Non-small Cell Lung Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07412041

Recruiting

MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)

for
Non-small Cell Lung Cancer
Location: Moncton, Chicoutimi, Montreal
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07431827

Phase3, Recruiting

First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Non-small Cell Lung Cancer, EGFR Mutation,
Location: Nashville TN
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT05099172

Phase1, Phase2, Recruiting

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

for
Carcinoma, Non-Small-Cell Lung, Lung Cancer (NSCLC),
Location: Athens GA, Knoxville TN, Huntsville AL, Hinsdale IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07489066

Phase2, Recruiting

A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation

for
Non-small Cell Lung Cancer (NSCLC)
Location: Edison NJ, Arlington VA, Glendale CA, San Francisco CA
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07566052

Phase3, Recruiting

A Study Evaluating The Combination of Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, Metastatic Lung Cancer
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT07603856

Phase2, Recruiting

A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.

for
Non Small Cell Lung Cancer (Squamous or Non Squamous),
Location: Mineola NY, White Plains NY, The Bronx NY, New York NY,
Sponsor: Eikon Therapeutics

Sex: All

Age: 18+

Code: NCT07365319

Phase2, Phase3, Recruiting

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

for
Advanced Solid Tumor, Non-Small Cell Lung Cancer,
Location: Fairfax VA, Tampa FL, Sarasota FL
Sponsor: Blueprint Medicines Corporation

Sex: All

Age: 18+

Code: NCT07629960

Phase1, Phase2, Recruiting

A Study of Ivonescimab in People With Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07594522

Phase1, Phase2, Recruiting

Lorlatinib Plus Local Consolidation Therapy In ALK Positive Advanced Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07415005

Phase2, Recruiting

A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07535437

Phase1, Phase2, Recruiting

A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07535463

Phase1, Phase2, Recruiting

Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

for
Breast Cancer (Triple Negative Breast Cancer (TNBC)),
Location: Nashville TN
Sponsor: Jessica Mezzanotte Sharpe

Sex: All

Age: 18+

Code: NCT07555210

Recruiting