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A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Manahawkin NJ, Fairfax VA, Weston FL, Pittsburgh PA,
Sponsor: Wayshine Biopharm, Inc.

Sex: All

Age: 18+

Code: NCT06868485

Phase2, Recruiting

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for
Non-small Cell Lung Cancer, Colorectal Carcinoma,
Location: Boston MA, New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06218914

Phase1, Recruiting

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for
Urothelial Carcinoma Bladder,
Location: New York NY, Glen Burnie MD, Miami FL, Pittsburgh PA,
Sponsor: Aktis Oncology, Inc.

Sex: All

Age: 18+

Code: NCT07020117

Phase1, Recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

for
ER+, HER 2- Breast Cancer, Non-small Cell Lung Cancer (NSCLC),
Location: Lake Success NY, East Brunswick NJ, Fairfax VA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18 - 70+

Code: NCT07540572

Phase1, Recruiting

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: New York NY, Columbus OH, Grand Rapids MI,
Sponsor: Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05985655

Phase1, Phase2, Recruiting

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Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Boston MA, New York NY, Montreal, Washington D.C. DC,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT07154706

Phase3, Recruiting

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma,
Location: Toronto, Dallas TX, San Antonio TX
Sponsor: Auricula Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07148128

Phase1, Phase2, Recruiting

NBTXR3 With Radiation Therapy Alone for Locally-advanced Non-small Cell Lung Cancer

for
Locally-Advanced Non-Small Cell Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07224152

Phase1, Phase2, Recruiting

Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Milford DE, Dover DE, Elk Grove Village IL, Houston TX,
Sponsor: N-Power Medicine

Sex: All

Age: 18+

Code: NCT07028489

Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for
Metastatic Solid Tumor, Recurrent Solid Tumor,
Location: Boston MA, New York NY, Cleveland OH, Grand Rapids MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06465069

Phase1, Recruiting

Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1

for
Non-small Cell Lung Cancer
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 19+

Code: NCT06579196

Phase1, Phase2, Recruiting

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

for
Non Small Cell Lung Cancer
Location: Detroit MI
Sponsor: Nerissa T. Viola

Sex: All

Age: 18+

Code: NCT06439914

Phase1, Recruiting

A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)

for
Non Small Cell Lung Cancer
Location: New York NY
Sponsor: Dizal Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06905197

Phase1, Recruiting

Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Boston MA, Philadelphia PA, Arlington VA, Fairfield OH,
Sponsor: BicycleTx Limited

Sex: All

Age: 18+

Code: NCT06933329

Phase2, Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

for
Melanoma, Medullary Thyroid Cancer,
Location: Tucson AZ, Seattle WA
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06814496

Phase1, Phase2, Recruiting

A Study Evaluating Neoadjuvant Chemoimmunotherapy With Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Bel Air MD, Glen Burnie MD, Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06800339

Phase1, Recruiting

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non Small Cell Lung Cancer,
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07020221

Phase1, Phase2, Recruiting

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

for
Soft-tissue Sarcoma, Triple Negative Breast Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07064018

Phase1, Phase2, Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

for
Epidermal Growth Factor, Epidermal Growth Factor Receptor,
Location: Lake Success NY, East Brunswick NJ, Nashville TN,
Sponsor: EpiBiologics

Sex: All

Age: 18+

Code: NCT07462377

Phase1, Recruiting

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

for
Melanoma, Non-small Cell Lung Cancer,
Location: Fairfax VA, Pittsburgh PA, Grand Rapids MI, St Louis MO,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07115043

Phase1, Phase2, Recruiting