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Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC

for
NSCLC Stage IV, NSCLC, Recurrent
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT04467723

Phase1, Phase2, Recruiting

Insomnia in Patients With Metastatic Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06472804

Recruiting

Ipatasertib and Docetaxel in Metastatic NSCLC Patients Who Have Failed 1st Line Immunotherapy

for
NSCLC Stage IV, NSCLC Stage IIIB
Location: Kansas City KS, Fairway KS
Sponsor: Jun Zhang, MD, PhD

Sex: All

Age: 18+

Code: NCT04467801

Phase2, Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors, HNSCC, SCLC, NSCLC,
Location: Boston MA, New York NY, New Haven CT, Miami FL, Toronto,
Sponsor: Tubulis GmbH

Sex: All

Age: 18+

Code: NCT06657222

Phase1, Phase2, Recruiting

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

for
Lung Cancer, Non-small Cell, Lung Cancer Metastatic,
Location: Weston FL, Canton OH, Cleveland OH, Detroit MI,
Sponsor: Krystal Biotech, Inc.

Sex: All

Age: 18+

Code: NCT06228326

Phase1, Phase2, Recruiting

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Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

for
Lung Carcinoma, Lung Non-Small Cell Carcinoma,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT05802186

Recruiting

Immune Profile Selection By Fraction of ctDNA in Patients With Advanced NSCLC Treated With Immunotherapy

for
Carcinoma, Non-Small-Cell Lung
Location: Hackensack NJ
Sponsor: Hackensack Meridian Health

Sex: All

Age: 18+

Code: NCT05715229

Phase2, Recruiting

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

for
Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations,
Location: Boston MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT05967689

Phase2, Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Montreal, Fairfax VA, Toronto, Cleveland OH, Detroit MI,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05208762

Phase1, Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung,
Location: Boston MA, Montreal, Baltimore MD, Ottawa, Toronto,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT06131840

Phase1, Recruiting

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT04151940

Recruiting

SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT05570825

Phase2, Recruiting

Study of a Tiotropium Inhaler For Shortness of Breath in Advanced Non-Small Cell Lung Cancer

for
NSCLC, Dyspnea
Location: Hamilton
Sponsor: Hamilton Health Sciences Corporation

Sex: All

Age: 18+

Code: NCT01172925

Phase2, Recruiting

Using Ex Vivo Tumoroids To Predict Immunotherapy Response In NSCLC

for
Lung Cancer, NSCLC, NSCLC Stage IV
Location: Kansas City KS, Fairway KS
Sponsor: Jun Zhang, MD, PhD

Sex: All

Age: 18 - 70+

Code: NCT05332925

Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

for
NSCLC, HNSCC, Melanoma, Metastatic Cancer, Advanced Solid Tumor,
Location: Pittsburgh PA, Irvine CA
Sponsor: CJ Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05877430

Phase1, Phase2, Recruiting

Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer

for
Resectable Lung Non-Small Cell Carcinoma
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06008730

Phase2, Recruiting

Gilteritinib for the Treatment of ALK NSCLC

for
Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT06225427

Phase1, Recruiting

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

for
Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8
Location: Columbus OH, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06139627

Recruiting

Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06249282

Phase1, Recruiting

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for
Advanced Colorectal Carcinoma,
Location: Lake Success NY, New York NY, Millville DE,
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT06073431

Recruiting