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Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

for
Stage III Lung Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04892953

Phase2, Recruiting

Confocal Laser Endomicroscopy VERification

for
Lung Cancer, Lung Neoplasm Malignant,
Location: New York NY
Sponsor: Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Sex: All

Age: 18+

Code: NCT06079970

Recruiting

Development and Analysis of a Stool Bank for Cancer Patients

for
Carcinoma, Non-Small-Cell Lung, Carcinoma, Colorectal
Location: Winter Haven FL, Fountain Valley CA
Sponsor: Persephone Biosciences

Sex: All

Age: 18+

Code: NCT04291755

Recruiting

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05501665

Phase1, Phase2, Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

for
Solid Tumor, Advanced Solid Tumor, Solid Tumor, Adult,
Location: Boston MA, Hackensack NJ, Philadelphia PA, Fairfax VA,
Sponsor: NiKang Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06586957

Phase1, Recruiting

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A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

for
Ovarian Neoplasms, Endometrial Neoplasms,
Location: Mineola NY, New York NY, Columbus OH, Grand Rapids MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06400472

Phase1, Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 16+

Code: NCT05269381

Phase1, Phase2, Recruiting

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Commack NY, Uniondale NY, Mineola NY, Harrison NY,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06500481

Phase3, Recruiting

The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors

for
Non-Small-Cell Lung Carcinoma, Malignant Melanoma,
Location: Elizabethtown KY
Sponsor: VastBiome

Sex: All

Age: 18+

Code: NCT05037825

Recruiting

Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

for
Large Cell Neuroendocrine Carcinoma,
Location: Princeton NJ, Glen Burnie MD, Cleveland OH, Atlanta GA,
Sponsor: Molecular Partners AG

Sex: All

Age: 18+

Code: NCT07278479

Phase1, Phase2, Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

for
Advanced Biliary Tract Carcinoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07405086

Recruiting

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

for
Non-Small-Cell Lung, Esophageal Cancer, Cutaneous Melanoma
Location: New Haven CT, Trumbull CT, Fairfax VA, Nashville TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07519655

Phase1, Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for
Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: Plexium, Inc.

Sex: All

Age: 18+

Code: NCT07284186

Phase1, Recruiting

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

for
Small Cell Lung Carcinoma,
Location: Boston MA, Montreal, Royal Oak MI, Iowa City IA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07006727

Phase1, Recruiting

Intratumoral N17350 in Advanced Solid Tumors

for
Neoplasms, Solid Tumor, Breast Neoplasms, Triple-Negative,
Location: Buffalo NY
Sponsor: Onchilles Pharma Inc

Sex: All

Age: 18+

Code: NCT07339176

Phase1, Phase2, Recruiting

Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

for
Clinical Stage 0 Cutaneous Melanoma AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03819296

Phase1, Recruiting

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

for
Metastatic Castration Resistant Prostate Cancer (mCRPC),
Location: Myrtle Beach SC, Nashville TN, Omaha NE, Irving TX,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT03460977

Phase1, Recruiting

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for
Breast Carcinoma, Colorectal Carcinoma,
Location: Rockport ME, Belfast ME, Brunswick ME, Augusta ME,
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06418204

Recruiting

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

for
Early Stage Triple-Negative Breast Carcinoma,
Location: Jacksonville FL, Rochester MN, Phoenix AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06349642

Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

for
Advanced Esophageal Squamous Cell Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06265285

Phase2, Recruiting