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At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase2, Recruiting

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

for
Breast Cancer, Sarcoma, Gastric Cancer, Lung Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06580002

Phase2, Recruiting

Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial

for
Lung Carcinoma, Stage I Lung Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04789681

Phase2, Recruiting

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

for
Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT04067830

Phase2, Recruiting

A Study of PHN-012 in Patients With Advanced Solid Tumors

for
Colon Cancer, Pancreatic Cancer, Lung Cancer (NSCLC),
Location: Boston MA, Washington D.C. DC, Fairfax VA, Durham NC,
Sponsor: Pheon Therapeutics

Sex: All

Age: 18+

Code: NCT07127874

Phase1, Recruiting

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Integrated Cancer Repository for Cancer Research

for
Pancreatic Cancer, Thyroid Cancer, Lung Cancer,
Location: Manchester CT, Holyoke MA, Glens Falls NY, Utica NY,
Sponsor: University of Nebraska

Sex: All

Age: 19 - 70+

Code: NCT02012699

Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for
Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer,
Location: Montreal, Hershey PA, Chapel Hill NC, Toronto,
Sponsor: Apollomics Inc.

Sex: All

Age: 18+

Code: NCT03175224

Phase2, Recruiting

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

for
Advanced/Metastatic Solid Tumors, Colorectal Cancer,
Location: Boston MA, New York NY, Philadelphia PA, Syracuse NY,
Sponsor: Merus B.V.

Sex: All

Age: 18+

Code: NCT03526835

Phase1, Phase2, Recruiting

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

for
HNSCC, ESCC, Esophageal Adenocarcinoma, Gastric Adenocarcinoma,
Location: Boston MA, New Haven CT, Hackensack NJ, Philadelphia PA,
Sponsor: Normunity AccelCo, Inc.

Sex: All

Age: 18+

Code: NCT07182149

Phase1, Recruiting

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Melanoma, HNSCC, Sarcoma, Squamous Cell Carcinoma,
Location: Boston MA, Fairfax VA, Pittsburgh PA, Dallas TX
Sponsor: ImmVira Pharma Co. Ltd

Sex: All

Age: 18+

Code: NCT04370587

Phase1, Phase2, Recruiting

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for
Advanced Solid Tumor, Ovarian Cancer, Endometrial Cancer, NSCLC
Location: New York NY, Fairfax VA, Cleveland OH, Lexington KY,
Sponsor: TORL Biotherapeutics, LLC

Sex: All

Age: 18+

Code: NCT05103683

Phase1, Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for
Oncology, MEK Mutation, RAF Gene Mutation,
Location: New York NY, Fairfax VA, Buffalo NY, Pittsburgh PA,
Sponsor: Nested Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06326411

Phase1, Recruiting

ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC

for
Solid Tumors, EGFR Exon 20 Insertion Mutations, NSCLC,
Location: New York NY, Fairfax VA
Sponsor: ORIC Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06816992

Phase1, Recruiting
Featured

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for
Non-Small Cell Lung Cancer,
Location: Montreal, Fairfax VA, Durham NC, Toronto,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT05005403

Phase1, Recruiting
Featured

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for
Non-Squamous Non-Small Cell Lung Cancer
Location: Ottawa, Fairfax VA, Orange City FL, Houston TX,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07005102

Phase2, Phase3, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: New York NY, Philadelphia PA, Nashville TN, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase1, Recruiting
New

Effects of Infusion Timing on Treatment Response in Solid Tumors

for
Lung Cancer, Non-small Cell Lung Cancer, Metastatic Lung Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07630168

Phase2, Recruiting

TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma

for
Renal Cell Cancer, Castrate Resistant Prostate Cancer,
Location: Houston TX, Los Angeles CA
Sponsor: Portage Biotech

Sex: All

Age: 18+

Code: NCT04969315

Phase1, Phase2, Recruiting

The Effect of Beta-glucan in Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT00682032

Recruiting

Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer

for
Non-small Cell Lung Cancer
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT02570815

Phase1, Recruiting