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Study of PF-07248144 in Advanced or Metastatic Solid Tumors

for
Locally Advanced or Metastatic ER+ HER2- Breast Cancer,
Location: New Haven CT, Edgewood KY, Louisville KY, Nashville TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT04606446

Phase2, Recruiting

CSF Analysis in EGFR Mutant Non-Small Cell Lung Cancer with Leptomeningeal Disease

for
EGFR Activating Mutation, Leptomeningeal Metastasis,
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT05257967

Recruiting

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

for
Non-small Cell Lung Cancer
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT04332367

Phase2, Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase1, Phase2, Recruiting

Study of Healthy Donor FMT (hdFMT) and Pembrolizumab in Relapsed/Refractory (R/R) PD-L1 Positive NSCLC

for
Non Small Cell Lung Cancer
Location: Pittsburgh PA
Sponsor: Diwakar Davar

Sex: All

Age: 18+

Code: NCT05669846

Phase2, Recruiting

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Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

for
Non-small Cell Lung Cancer
Location: Winston-Salem NC, Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06567704

Recruiting

Pan-tumor MRD Study

for
Muscle Invasive Bladder Urothelial Carcinoma, Esophageal Cancer,
Location: Maumee OH, San Diego CA
Sponsor: Flatiron Health

Sex: All

Age: 18+

Code: NCT06605404

Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for
Solid Tumors With HRAS Alterations,
Location: Boston MA, New Brunswick NJ, Pittsburgh PA,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06026410

Phase1, Recruiting

Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer, Lung Cancer
Location: Los Angeles CA, Beverly Hills CA, Torrance CA
Sponsor: Karen Reckamp, MD, MS

Sex: All

Age: 18+

Code: NCT05401110

Phase1, Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for
Non-Small Cell Lung Cancer
Location: Milford MA, Weymouth MA, Brighton MA, Boston MA,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT06767514

Phase3, Recruiting

GEMINI-NSCLC: NSCLC Biomarker Study

for
Non-Small Cell Lung Cancer
Location: Norwich CT, White Plains NY, New York NY, Belleville NJ,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05236114

Recruiting

Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection

for
Lung Cancer Patients, Non-small Cell Lung Cancer (NSCLC)
Location: Toronto
Sponsor: Marc de Perrot

Sex: All

Age: 18 - 70+

Code: NCT06331455

Phase2, Recruiting

Using ctDNA to Determine Therapies for Lung Cancer

for
Non Small Cell Lung Cancer, Complete Surgical Resection,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04966663

Phase2, Recruiting

Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer

for
Non-small Cell Lung Cancer, Advanced Pancreatic Adenocarcinoma,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04789486

Phase1, Phase2, Recruiting

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for
Non-small Cell Lung Cancer
Location: New York NY, Lancaster PA, Greenville NC, Syracuse NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06561386

Phase3, Recruiting

I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy

for
Non Small Cell Lung Cancer, Lung Cancer Metastatic,
Location: Chicago IL
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Sex: All

Age: 18+

Code: NCT05537922

Recruiting

Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy

for
Lung Cancer, Pneumonitis, Radiation-Induced Lung Injury,
Location: Camden NJ
Sponsor: The Cooper Health System

Sex: All

Age: 18+

Code: NCT06688422

Recruiting

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

for
Advanced or Metastatic Solid Tumors, Non Small Cell Lung Cancer,
Location: Boston MA, New Haven CT, Fairfax VA, Nashville TN,
Sponsor: Incendia Therapeutics

Sex: All

Age: 18+

Code: NCT05753722

Phase1, Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

for
Advanced Solid Tumor, Metastatic Cancer, Cutaneous Melanoma,
Location: Morristown NJ, Miami FL, Huntersville NC,
Sponsor: Aulos Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05267626

Phase1, Phase2, Recruiting

Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Baltimore MD, Pinehurst NC, Athens GA, Glendale CA
Sponsor: Teligene US

Sex: All

Age: 18+

Code: NCT05168566

Phase2, Recruiting