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First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for
Advanced Solid Tumor, Ovarian Cancer, Endometrial Cancer, NSCLC
Location: New York NY, Fairfax VA, Cleveland OH, Lexington KY,
Sponsor: TORL Biotherapeutics, LLC

Sex: All

Age: 18+

Code: NCT05103683

Phase1, Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for
Oncology, MEK Mutation, RAF Gene Mutation,
Location: New York NY, Fairfax VA, Buffalo NY, Pittsburgh PA,
Sponsor: Nested Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06326411

Phase1, Recruiting

ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC

for
Solid Tumors, EGFR Exon 20 Insertion Mutations, NSCLC,
Location: New York NY, Fairfax VA
Sponsor: ORIC Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06816992

Phase1, Recruiting
Featured

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for
Non-Small Cell Lung Cancer,
Location: Montreal, Fairfax VA, Durham NC, Toronto,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT05005403

Phase1, Recruiting
Featured

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for
Non-Squamous Non-Small Cell Lung Cancer
Location: Ottawa, Fairfax VA, Orange City FL, Houston TX,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07005102

Phase2, Phase3, Recruiting

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Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: New York NY, Philadelphia PA, Nashville TN, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase1, Recruiting
New

Effects of Infusion Timing on Treatment Response in Solid Tumors

for
Lung Cancer, Non-small Cell Lung Cancer, Metastatic Lung Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07630168

Phase2, Recruiting

TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma

for
Renal Cell Cancer, Castrate Resistant Prostate Cancer,
Location: Houston TX, Los Angeles CA
Sponsor: Portage Biotech

Sex: All

Age: 18+

Code: NCT04969315

Phase1, Phase2, Recruiting

The Effect of Beta-glucan in Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT00682032

Recruiting

Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer

for
Non-small Cell Lung Cancer
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT02570815

Phase1, Recruiting

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

for
Lung Cancer, Small Cell Lung Carcinoma,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05620342

Early_phase1, Recruiting

Dabrafenib and/or Trametinib Rollover Study

for
Melanoma, Non Small Cell Lung Cancer, Solid Tumor, Rare Cancers,
Location: Toronto
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT03340506

Recruiting

Previously Untreated Advanced Non-Small Cell Lung Cancer (NSCLC)

for
Untreated Advanced Non-Small Cell Lung Cancer
Location: Voorhees NJ
Sponsor: The Cooper Health System

Sex: All

Age: 18+

Code: NCT00254319

Phase2, Recruiting

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT01639508

Phase2, Recruiting

A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: New York City NY, Louisville KY, Nashville TN, Omaha NE,
Sponsor: Avistone Biotechnology Co., Ltd.

Sex: All

Age: 18+

Code: NCT06046495

Phase1, Recruiting

Safety and Efficacy of Talactoferrin in Addition to Standard Chemotherapy in Patients With Non-small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Bronx NY, Durham NC, Chattanooga TN, Nashville TN,
Sponsor: Agennix

Sex: All

Age: 18+

Code: NCT00706862

Phase3, Recruiting

A Study Evaluating MM-310 in Patients With Solid Tumors

for
Solid Tumors, Urothelial Carcinoma, Gastric Carcinoma,
Location: Durham NC, Buffalo NY, Rochester MN, Scottsdale AZ,
Sponsor: Merrimack Pharmaceuticals

Sex: All

Age: 18+

Code: NCT03076372

Phase1, Recruiting

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

for
Biliary Tract Cancer, Breast Cancer, Cervical Cancer,
Location: Boston MA, Miami FL, Denver CO, Nashville TN,
Sponsor: ModeX Therapeutics, An OPKO Health Company

Sex: All

Age: 18+

Code: NCT06239194

Phase1, Phase2, Recruiting

A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors

for
Solid Tumor, Renal Cell Cancer Metastatic,
Location: Philadelphia PA, Dallas TX
Sponsor: Eutilex

Sex: All

Age: 18+

Code: NCT04903873

Phase1, Phase2, Recruiting

A First-in-Human Study of CKD-703 in Advanced Solid Tumors and Non-Small Cell Lung Cancer

for
Advanced Solid Tumors, Non-Small Cell Lung Cancer
Location: Ohio City OH
Sponsor: Chong Kun Dang Pharmaceutical

Sex: All

Age: 19+

Code: NCT07439094

Phase1, Phase2, Recruiting