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3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

for
Head and Neck Squamous Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05674396

Phase2, Recruiting

Cancer in Inherited Bone Marrow Failure Syndromes

for
Diamond Blackfan Anemia, Dyskeratosis Congenita, Fanconi Anemia,
Location: Bethesda MD, Rockville MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 70+

Code: NCT00027274

Recruiting

Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT

for
Head and Neck Cancer, Body Image Disturbance, Body Image,
Location: Hershey PA, Charleston SC, Detroit MI, St Louis MO,
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05442957

Recruiting

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: Clasp Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06778863

Phase1, Recruiting

HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers

for
Squamous Cell Carcinoma of Head and Neck
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06487403

Recruiting

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Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors

for
Metastatic Pancreatic Neuroendocrine Tumor
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06663072

Phase1, Recruiting

Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 18+

Code: NCT05132504

Phase2, Recruiting

A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Detroit MI, Houston TX
Sponsor: Oncotelic Inc.

Sex: All

Age: 18+

Code: NCT06079346

Phase2, Phase3, Recruiting

Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

for
HPV-unrelated Head and Neck Squamous Cell Carcinoma
Location: St Louis MO, Fargo ND, Sioux Falls SD
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT04966481

Phase3, Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

for
Advanced Endometrial Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05039801

Phase1, Recruiting

18F-DOPA II - PET Imaging Optimization

for
Congenital Hyperinsulinism, Neuroblastoma, Parkinson Disease,
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 0+

Code: NCT04706910

Phase3, Recruiting

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06088381

Phase2, Recruiting

A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

for
Recurrent Head and Neck Squamous Cell Carcinoma
Location: Providence RI, Philadelphia PA, Miami FL, Tampa FL,
Sponsor: Rakuten Medical, Inc.

Sex: All

Age: 18+

Code: NCT06699212

Phase3, Recruiting

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

for
Duodenal Neoplasm, Pancreatic Neoplasm
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT06411795

Phase2, Recruiting

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

for
Malignant Head and Neck Neoplasm, Malignant Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT01365169

Recruiting

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

for
VHL Pancreatic Neuroendocrine Tumors, Von Hippel-Lindau Disease,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT04074135

Phase2, Recruiting

A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment

for
Locally Advanced Pancreatic Adenocarcinoma
Location: Montreal, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06453486

Phase2, Recruiting

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

for
Head and Neck Squamous Cell Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06597565

Phase2, Recruiting

Molecular and Genomic Profiling of Head and Neck Tumors

for
Head and Neck Neoplasms
Location: The Bronx NY
Sponsor: Montefiore Medical Center

Sex: All

Age: 0+

Code: NCT00200486

Recruiting

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC),
Location: Pittsburgh PA
Sponsor: Dan Zandberg

Sex: All

Age: 18+

Code: NCT06052839

Phase2, Recruiting