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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for
Non Small Cell Lung Cancer, Lung Cancer, Breast Cancer,
Location: Boston MA, New Haven CT, New York NY,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT05983432

Phase1, Recruiting

Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

for
Triple Negative Breast Cancer, Non Small Cell Lung Cancer,
Location: Hartford CT, Commack NY, Norwalk CT, Uniondale NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT03808337

Phase2, Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

for
Non Small Cell Lung Cancer
Location: Westbrook ME, Stony Brook NY, Stamford CT,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312137

Phase3, Recruiting

Stereotactic Radiotherapy (SBRT) of Lung Metastasis

for
Non-small Cell Lung Cancer, Metastasis From Other Cancers
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT01803542

Phase2, Recruiting

Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects

for
Non Small Cell Lung Cancer
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06221800

Recruiting

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

for
Non-Small Cell Lung Cancer
Location: Burlington MA, Hartford CT, New Haven CT, Lebanon NH,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT05899608

Phase3, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Sydney, Saint John, Scarborough ME, West Haven CT,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06692738

Phase3, Recruiting

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

for
Squamous Cell Carcinoma, Nonmelanoma Skin Cancer,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT05108090

Recruiting

A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06122064

Recruiting

KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC

for
Non-Small Cell Lung Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18 - 70+

Code: NCT05254184

Phase1, Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for
Diffuse Astrocytoma, IDH-Mutant, Glioblastoma, IDH-wildtype,
Location: Boston MA, Boynton Beach FL, Nashville TN, Dallas TX,
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06047379

Phase1, Phase2, Recruiting

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

for
Recurrent Adenoid Cystic Carcinoma of the Oral Cavity,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT01473784

Recruiting

Ontario-wide Cancer TArgeted Nucleic Acid Evaluation

for
Breast Cancer, Lung Cancer, Colorectal Cancer, Melanoma,
Location: Ottawa, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT02906943

Recruiting

Locally Ablative TherapY in Oligo-ProgressiVe GEnitourinary TumoRs (LAYOVER)

for
Prostate Cancer, Oligoprogressive, Urothelial Carcinoma,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06101290

Recruiting

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Boston MA, New Haven CT, New York NY, Tampa FL,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06917079

Phase1, Recruiting

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Boston MA, Westbury NY, New York NY, Washington D.C. DC,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06162221

Phase1, Phase2, Recruiting

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

for
Oropharyngeal Squamous Cell Carcinoma (OPSCCA),
Location: Philadelphia PA
Sponsor: Ryan Carey

Sex: All

Age: 18+

Code: NCT06747390

Phase1, Recruiting

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

for
Non Small Cell Lung Cancer, Triple Negative Breast Cancer,
Location: Boston MA, Buffalo NY, Orlando FL, Sarasota FL,
Sponsor: Compass Therapeutics

Sex: All

Age: 18+

Code: NCT06150664

Phase1, Recruiting

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

for
Platinum-resistant Ovarian Cancer, Recurrent Ovary Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18 - 70+

Code: NCT06321484

Phase1, Recruiting

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer,
Location: New Haven CT, Norwalk CT, New York NY, Montreal,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06343402

Phase1, Recruiting