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Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT01639508

Phase2, Recruiting

Dabrafenib and/or Trametinib Rollover Study

for
Melanoma, Non Small Cell Lung Cancer, Solid Tumor, Rare Cancers,
Location: Toronto
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT03340506

Recruiting

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

for
Kidney Cancer, Renal Cell Carcinoma, Clear Cell Carcinoma,
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18+

Code: NCT04623502

Recruiting

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

for
Lung Cancer, Small Cell Lung Carcinoma,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05620342

Early_phase1, Recruiting

Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer

for
Non-small Cell Lung Cancer
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT02570815

Phase1, Recruiting

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TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma

for
Renal Cell Cancer, Castrate Resistant Prostate Cancer,
Location: Houston TX, Los Angeles CA
Sponsor: Portage Biotech

Sex: All

Age: 18+

Code: NCT04969315

Phase1, Phase2, Recruiting
New

Effects of Infusion Timing on Treatment Response in Solid Tumors

for
Lung Cancer, Non-small Cell Lung Cancer, Metastatic Lung Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07630168

Phase2, Recruiting
New

A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1)

for
Small Cell Lung Cancer (SCLC ),
Location: New York NY, Hackensack NJ, Nashville TN, St Louis MO,
Sponsor: Moonlight Bio, Inc

Sex: All

Age: 18+

Code: NCT07488923

Phase1, Recruiting

Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures

for
Hip Fractures, Surgical Blood Loss
Location: Corvallis OR
Sponsor: Good Samaritan Regional Medical Center, Oregon

Sex: All

Age: 18+

Code: NCT02580227

Recruiting

Trikafta Exercise Study in Cystic Fibrosis

for
Cystic Fibrosis, Lung Diseases
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 19+

Code: NCT05279040

Recruiting

Sinus Disease in Young Children With Cystic Fibrosis

for
Cystic Fibrosis in Children, Cystic Fibrosis,
Location: Colchester VT, Charlottesville VA, Cincinnati OH,
Sponsor: University of California, Los Angeles

Sex: All

Age: 2 - 8

Code: NCT06191640

Recruiting

The Impact of Two Different Physical Therapy Programs in the Rehabilitation of Patients Undergoing Anterior Approach Hip Replacement Surgery

for
Hip Arthritis, Total Hip Arthroplasty
Location: Somerset NJ, Somerville NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT04492462

Recruiting

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

for
Hip Dysplasia
Location: Iowa City IA
Sponsor: Michael C Willey

Sex: All

Age: 13 - 50

Code: NCT06519955

Phase2, Phase3, Recruiting

Digital Sizing for Orthopaedic Hip Implants

for
Hip Arthritis
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 0+

Code: NCT00665210

Recruiting

Impact of Sinus Surgery on Individuals With Cystic Fibrosis

for
Chronic Rhinosinusitis (Diagnosis), Cystic Fibrosis
Location: Chapel Hill NC, Charleston SC, Nashville TN, Aurora CO,
Sponsor: University of California, Los Angeles

Sex: All

Age: 18 - 70+

Code: NCT04469439

Recruiting

Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis

for
Cystic Fibrosis, Ventilatory Defect
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 70+

Code: NCT06057714

Recruiting

19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease

for
Cystic Fibrosis in Children
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 6 - 17

Code: NCT06066723

Recruiting

The WHERE Study: Waiting for Hip and KneE REplacement

for
Hip Osteoarthritis, Knee Osteoarthritis
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT06074900

Recruiting

Artificial Intelligence (AI) Cytopathology Trial

for
Pancreatic Solid Lesions
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18 - 70+

Code: NCT05018663

Recruiting

Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study

for
Cervicogenic Headache, Neck Pain, Whiplash,
Location: Chesterfield MO
Sponsor: Logan College of Chiropractic

Sex: All

Age: 18 - 65

Code: NCT00510757

Recruiting