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Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

for
Ewing Sarcoma, Rhabdomyosarcoma, Wilms Tumor, Neuroblastoma,
Location: Valhalla NY
Sponsor: New York Medical College

Sex: All

Age: 1 - 30

Code: NCT04308330

Phase1, Recruiting

AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL

for
Large B-cell Lymphoma
Location: Ottawa, Calgary
Sponsor: AstraZeneca

Sex: All

Age: 65 - 70+

Code: NCT07215585

Phase3, Recruiting

Registry of Older Patients With Cancer

for
Chronic Myeloproliferative Disorders,
Location: Morehead City NC, New Bern NC, Greenville NC,
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 65+

Code: NCT01137825

Recruiting

Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource

for
Plasma Cell Dyscrasias,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT01408225

Recruiting

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

for
Peripheral T-Cell Lymphoma, Not Otherwise Specified,
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06561048

Phase3, Recruiting

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Pembro Plus CAR T-cell Therapy in R/R in PMBCL

for
Primary Mediastinal Large B-cell Lymphoma (PMBCL),
Location: Boston MA, New York NY
Sponsor: Jennifer Crombie, MD

Sex: All

Age: 18+

Code: NCT05934448

Phase2, Recruiting

Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies

for
Hematologic Malignancy, Large B-cell Lymphoma,
Location: Los Angeles CA
Sponsor: Joshua Sasine, MD, PhD

Sex: All

Age: 18 - 70+

Code: NCT05887167

Phase1, Recruiting

A Study of Bexarotene Combined With Radiotherapy in People With Mycosis Fungoides

for
Cutaneous T-cell Lymphoma
Location: Commack NY, Rockville Centre NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05296304

Phase1, Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for
Carcinoma, Non-Small-Cell Lung
Location: White Plains NY, Schenectady NY, Montreal, Newark DE,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06875310

Phase3, Recruiting

Allo HSCT for High Risk Hemoglobinopathies

for
Graft Failure, Sickle Cell Disease, Hemoglobinopathies
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0 - 55

Code: NCT06872333

Phase2, Recruiting

IS-free Treg HaploHCT

for
Stem Cell Transplant Complications, Graft Vs Host Disease,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18 - 70+

Code: NCT04678401

Phase1, Recruiting

MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma

for
Autologous Stem Cell Transplant, Classic Hodgkin Lymphoma
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT06377540

Phase2, Recruiting

Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells

for
Recurrent Diffuse Large B-Cell Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07042438

Phase2, Recruiting

A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma

for
Lymphoma, Lymphoma, Large B-Cell, Diffuse
Location: Boston MA, Miami FL
Sponsor: Jennifer Crombie, MD

Sex: All

Age: 18+

Code: NCT05800366

Phase2, Recruiting

A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies

for
Hematological Malignancies, B-cell Non-Hodgkin Lymphoma
Location: New York NY
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT07220616

Phase1, Phase2, Recruiting

AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

for
Lymphoma, Non-Hodgkin Lymphoma, Hodgkin Lymphoma,
Location: Boston MA, New York NY, Philadelphia PA, Miami FL,
Sponsor: AstraZeneca

Sex: All

Age: 12+

Code: NCT06137144

Phase1, Phase2, Recruiting

A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

for
Lymphomas, B-cell Lymphomas
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05773040

Phase1, Recruiting

BHB & CAR-T for Lymphomas

for
Large B-cell Lymphoma
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06610344

Recruiting

Evaluating the Safety and Efficacy of DuoCAR20.19.22-D95 in Adult Patients With Relapsed or Refractory B-cell Malignancies

for
B-Cell Non-Hodgkin Lymphoma,
Location: Westwood KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT06879340

Phase1, Recruiting

Cancer Genetic Testing in Ethnic Populations

for
Breast Carcinoma, Carcinoma of Unknown Primary,
Location: Jacksonville FL, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04475640

Recruiting