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Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

for
Acute Leukemia of Ambiguous Lineage,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0 - 65

Code: NCT06013423

Phase2, Recruiting

Hypofractionated Radiation Therapy for Merkel Cell Carcinoma

for
Merkel Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05100095

Phase2, Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

for
Obesity and Obesity-related Medical Conditions, Diabetes,
Location: Columbia MO
Sponsor: Bettina Mittendorfer

Sex: All

Age: 18 - 70+

Code: NCT07083557

Recruiting

Avo In R/R And Previously Untreated MCL

for
Mantle Cell Lymphoma, Refractory Lymphoma
Location: Boston MA, Chicago IL
Sponsor: Austin I Kim

Sex: All

Age: 18+

Code: NCT04855695

Phase1, Phase2, Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

for
B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma,
Location: Valhalla NY, Chapel Hill NC, Jacksonville FL,
Sponsor: Vironexis Biotherapeutics Inc.

Sex: All

Age: 13 - 70+

Code: NCT06533579

Phase1, Phase2, Recruiting

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PROMIS and Mobility Evaluation in Sarcoma Patients

for
Sarcoma, Giant Cell Tumor of Bone
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT07227961

Recruiting

BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma

for
Mantle Cell Lymphoma, Lymphoma
Location: Boston MA, New York NY, St Louis MO
Sponsor: Christine Ryan

Sex: All

Age: 18+

Code: NCT06854003

Phase2, Recruiting

Neoadjuvant Zanzalintinib Plus Nivolumab in Patients With Locally Advanced and/or Inoperable Clear Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis

for
Locally Advanced Renal Cell Carcinoma
Location: Richmond VA, St Louis MO, Dallas TX
Sponsor: Qian Qin

Sex: All

Age: 18+

Code: NCT06794229

Phase2, Recruiting

Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

for
Blastoid Variant Mantle Cell Lymphoma, Mantle Cell Lymphoma,
Location: New York NY, Salt Lake City UT, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT05861050

Phase1, Phase2, Recruiting

Pembrolizumab and Brentuximab Vedotin in Subjects With Relapsed/Refractory T-cell Lymphoma

for
T-Cell Lymphoma
Location: Boston MA, New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT05313243

Phase2, Recruiting

Two Step Haplo With Radiation Conditioning

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Philadephia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT05031897

Phase2, Recruiting

AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic Cancer

for
Borderline Resectable Pancreatic Ductal Adenocarcinoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07619313

Phase1, Recruiting

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma,
Location: Boston MA, Providence RI, New York NY, Hackensack NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06564038

Phase1, Phase2, Recruiting

A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHL

for
Hodgkin Lymphoma, B-Cell Lymphoma, Relapsed B-cell NHL
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05615636

Phase2, Recruiting

Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD

for
Lung Non-Small Cell Carcinoma
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07186699

Recruiting

PACIFIC: Primary Mediastinal Large B-cell Lymphoma Treated With Antibody Therapy, Checkpoint Inhibitor in Frontline With ImmunoChemotherapy

for
Ann Arbor Stage I Primary Mediastinal (Thymic) Large B-Cell Lymphoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04745949

Phase2, Recruiting

Phase 1 Trial of BTM-3566 in Relapsed/Refractory Mature B Cell Lymphomas

for
Lymphoma, B-Cell
Location: Charlotte NC, Houston TX
Sponsor: Bantam Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06792734

Phase1, Recruiting

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

for
Relapsed or Refractory CD19+ B-cell Lymphoma,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05963217

Phase1, Recruiting

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

for
DLBCL, Diffuse Large B-Cell Lymphoma
Location: Valhalla NY, Horsham PA, Boca Raton FL, Hialeah FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05139017

Phase2, Phase3, Recruiting

Pembrolizumab and Mogamulizumab in Advanced-stage, Relapsed/Refractory Cutaneous T-cell Lymphomas

for
Cutaneous T Cell Lymphoma, Fungoides Mycosis Sezary Syndrome
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT05956041

Phase2, Recruiting