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Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

for
Renal Cell Carcinoma
Location: Mineola NY, New York NY, Durham NC, Pittsburgh PA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18 - 70+

Code: NCT07049926

Phase1, Phase2, Recruiting

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

for
Metastatic Oral Cavity Carcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06997068

Phase2, Recruiting

Iadademstat + SBRT With Atezo in ES-SCLC

for
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07113691

Phase1, Recruiting

Odronextamab for the Treatment of Relapsed and Refractory Diffuse Large B-cell Lymphoma Before and After Chimeric Antigen Receptor T-cell Therapy

for
Recurrent Diffuse Large B-Cell Lymphoma,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06854159

Phase2, Recruiting

Imaging of Solid Tumors Using 18F-TRX

for
Solid Tumor, Solid Carcinoma,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT06942104

Phase1, Recruiting

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External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer

for
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06543576

Phase1, Phase2, Recruiting

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Charlottesville VA, Pittsburgh PA, Wesley Chapel FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07012031

Phase1, Phase2, Recruiting

Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer

for
Squamous Cell Cancer of Head and Neck (SCCHN)
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07348887

Recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Stony Brook NY, Lake Success NY, Rego Park NY,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06686771

Phase3, Recruiting

GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07017829

Phase2, Recruiting

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

for
Oral Cavity Squamous Cell Carcinoma,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT07121595

Phase2, Recruiting

ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx

for
Squamous Cell Carcinoma of Oropharynx, HPV Positive Cancer,
Location: Carmel IN, Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT06915038

Recruiting

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for
Lymphoma, Large B-Cell, Diffuse
Location: Boston MA, Westbury NY, Mineola NY, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06890884

Phase2, Recruiting

Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer

for
EGFR Mutation Positive Non-small Cell Lung Cancer,
Location: Calverton MD, Fairfax VA, Pittsburgh PA, Houston TX,
Sponsor: Nuvectis Pharma, Inc.

Sex: All

Age: 18+

Code: NCT07315113

Phase1, Recruiting

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8,
Location: Abington PA, Philadelphia PA, Willow Grove PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT05502523

Recruiting

Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers

for
Salivary Gland Cancer,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT05553782

Early_phase1, Recruiting

ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT06902272

Phase2, Recruiting

Study of CAR-T Therapy in Older Patients

for
Lymphoma, Refractory B-Cell Lymphoma, Lymphoma, B-Cell,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT04300998

Recruiting

Shortened Course of Radiation Therapy After Trans-oral Robotic Surgery in Patients With HPV-Mediated Oropharyngeal Squamous Cell Carcinoma.

for
Oropharyngeal Squamous Cell Carcinoma,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT07044635

Phase2, Recruiting

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

for
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma, RCC,
Location: New Haven CT, Lake Success NY, New York NY, Fairfax VA,
Sponsor: Neomorph, Inc

Sex: All

Age: 18+

Code: NCT07300241

Phase1, Recruiting