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Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas

for
Basal Cell Carcinoma (BCC)
Location: Phoenix AZ
Sponsor: Nathalie Zeitouni

Sex: All

Age: 18+

Code: NCT06623201

Phase1, Recruiting

Promoting Immunotherapy Efficacy With Low-Dose Liver RT

for
Low-Dose Liver Radiation (LD-LRT), Non Small Cell Lung Cancer,
Location: Cincinnati OH
Sponsor: Jordan Kharofa

Sex: All

Age: 18+

Code: NCT07225036

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

for
Advanced Solid Malignancies, Non-small Cell Lung Cancer (NSCLC),
Location: Baltimore MD, Fairfax VA, Toronto, San Antonio TX,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07223047

Phase1, Phase2, Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

for
Cancer, Immunotherapy, Advanced Solid Tumors Cancer,
Location: Frederick MD, St Louis MO, Springfield MO,
Sponsor: Elephas

Sex: All

Age: 18+

Code: NCT07327489

Recruiting

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06910761

Phase2, Recruiting

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Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer (SCLC)
Location: Virginia Beach VA, Norfolk VA, Chesapeake VA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07226999

Phase2, Phase3, Recruiting

An External Control Arm Study in Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Milford DE, Dover DE, Elk Grove IL, Rolling Meadows IL,
Sponsor: N-Power Medicine

Sex: All

Age: 18+

Code: NCT07174388

Recruiting

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

for
Soft-tissue Sarcoma, Triple Negative Breast Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07064018

Phase1, Phase2, Recruiting

Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

for
Oral Squamous Cell Carcinoma, Oral Cancer, Head and Neck Cancer,
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06627270

Phase2, Recruiting

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Brewer ME, Stony Brook NY, Long Branch NJ,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07195734

Phase2, Recruiting

Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

for
Cutaneous Squamous Cell Carcinoma of the Head and Neck,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06990737

Phase2, Recruiting

Toripalimab With Chemotherapy for Sinus Cancer

for
Sinonasal Cancer, Paranasal Sinus Neoplasms,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06940180

Phase2, Recruiting

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

for
Metastatic Pancreatic Ductal Adenocarcinoma,
Location: Miami FL
Sponsor: Benjamin Spieler

Sex: All

Age: 18+

Code: NCT06843551

Phase2, Recruiting

A Phase 1 Study of the Safety and Tolerability of CTX-10726

for
Gastroesophageal Cancer (GC), Hepatocellular Carcinoma (HCC),
Location: Lake Success NY, Pittsburgh PA, Greenville SC,
Sponsor: Compass Therapeutics

Sex: All

Age: 18+

Code: NCT07419841

Phase1, Recruiting

Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC

for
Squamous Cell Carcinoma, Head and Neck Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06137274

Phase2, Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

for
Small-cell Lung Cancer
Location: New Haven CT, Stony Brook NY, The Bronx NY, Broomall PA,
Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All

Age: 18+

Code: NCT07218146

Phase3, Recruiting

Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors

for
Hearing Loss, Metastatic Malignant Germ Cell Tumor,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: Male

Age: 18+

Code: NCT07218913

Phase1, Recruiting

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

for
Small Cell Lung Cancer Extensive Stage
Location: Hackensack NJ, Charlottesville VA, Orlando FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07227597

Phase1, Phase2, Recruiting

Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients

for
Radiation Lymphedema, Radiation Fibrosis, Head and Neck Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06708754

Recruiting

Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

for
Extensive Stage Lung Small Cell Cancer
Location: The Bronx NY, New Brunswick NJ, Morristown NJ,
Sponsor: PrECOG, LLC.

Sex: All

Age: 18+

Code: NCT07057791

Phase2, Recruiting