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Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

for
Stage III Lung Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04892953

Phase2, Recruiting

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

for
Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT06839053

Phase2, Recruiting

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

for
Relapsed Small Cell Lung Cancer,
Location: Philadelphia PA, Salisbury NC, Pittsburgh PA,
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT06681220

Phase1, Phase2, Recruiting

Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer

for
Cigarette Smoker, Current Smoker, Lung Adenocarcinoma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT03199651

Recruiting

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

for
Sinonasal Squamous Cell Carcinoma,
Location: Waterford CT, New Haven CT, Waterbury CT, Trumbull CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07281417

Phase2, Recruiting

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CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04892277

Phase1, Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

for
Endocrine Tumors, Non-Small Cell Lung Cancer, Ovarian Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03412877

Phase2, Recruiting

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

for
Central Nervous System Lymphoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05011045

Recruiting

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

for
Acquired Immunodeficiency Syndrome, BK Virus Infection,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT02479698

Phase2, Recruiting

Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

for
Metastatic Non-Squamous Non-Small Cell Lung Cancer,
Location: New Haven CT, New York NY, Durham NC, Charleston SC,
Sponsor: CatalYm GmbH

Sex: All

Age: 18+

Code: NCT07098988

Phase2, Recruiting

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07128680

Phase1, Recruiting

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Melanoma, HNSCC, Sarcoma, Squamous Cell Carcinoma,
Location: Boston MA, Fairfax VA, Pittsburgh PA, Dallas TX
Sponsor: ImmVira Pharma Co. Ltd

Sex: All

Age: 18+

Code: NCT04370587

Phase1, Phase2, Recruiting

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

for
B-Cell Non-Hodgkin Lymphoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06191887

Phase1, Recruiting

Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Columbus OH
Sponsor: Dwight Owen

Sex: All

Age: 18+

Code: NCT06616623

Phase1, Recruiting

Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer

for
Endometrial Clear Cell Adenocarcinoma,
Location: Maywood IL, Houston TX, Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 0+

Code: NCT03422198

Phase3, Recruiting

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

for
NK-Cell Lymphoma, NK-Cell Leukemia, Peripheral T Cell Lymphoma
Location: Valhalla NY, Columbus OH, Grand Rapids MI,
Sponsor: New York Medical College

Sex: All

Age: 1 - 31

Code: NCT03719105

Early_phase1, Recruiting

Tissue Collection for Studies of Lymph Cancer

for
Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT01676805

Recruiting

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

for
Renal Cell Carcinoma, Kidney Cancer, Kidney Neoplasm,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07397611

Phase2, Recruiting

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Boston MA, Baltimore MD, Washington D.C. DC, Fairfax VA,
Sponsor: Puma Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT06095505

Phase2, Recruiting

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

for
Breast Cancer, Sarcoma, Gastric (Stomach) Cancer, Lung Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07447050

Phase2, Recruiting