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Phase II Study of Salvage Radiation Treatment After B-cell Maturation Antigen Chimeric Antigen Receptor T-cell Therapy for Relapsed Refractory Multiple Myeloma

for
Multiple Myeloma, Plasma Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05336383

Phase2, Recruiting

Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

for
Hairy Cell Leukemia
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04322383

Phase2, Recruiting

Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)

for
Advanced Clear Cell Renal Carcinoma (Ccrcc),
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05665361

Phase1, Phase2, Recruiting

Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1

for
Synovial Sarcoma, Myxoid/Round Cell Liposarcoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 16 - 70+

Code: NCT06083883

Phase1, Recruiting

A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)

for
Non-Small Cell Lung Cancer
Location: Fairfax VA, Atlanta GA, Santa Monica CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07098338

Phase2, Recruiting

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Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

for
Breast Cancer (Triple Negative Breast Cancer (TNBC)),
Location: Nashville TN
Sponsor: Jessica Mezzanotte Sharpe

Sex: All

Age: 18+

Code: NCT07555210

Recruiting

Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours

for
Germ Cell Tumor
Location: Boston MA, New York NY, Baltimore MD, Columbus OH,
Sponsor: University of Sydney

Sex: All

Age: 11 - 50

Code: NCT02582697

Phase3, Recruiting

A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

for
Hepatotoxicity, Tenosynovial Giant Cell Tumor
Location: Boston MA, Columbus OH, Santa Monica CA
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT04635111

Recruiting

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

for
Small Cell Lung Cancer, SCLC,
Location: Charlottesville VA, Detroit MI, Indianapolis IN,
Sponsor: Hirva Mamdani

Sex: All

Age: 18+

Code: NCT05903092

Phase2, Recruiting

A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07535463

Phase1, Phase2, Recruiting

A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07535437

Phase1, Phase2, Recruiting

A Study of Axicabtagene Ciloleucel and Glofitamab as Second-Line Therapy for Relapsed or Refractory Patients With Large B Cell Lymphoma

for
B Cell Lymphoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06213311

Phase2, Recruiting

Study to Evaluate the Safety and Efficacy of Bicalutamide in Combination With Sunitinib in Patients With TKIs-resistant RCC

for
Carcinoma, Renal Cell
Location: Buffalo NY
Sponsor: State University of New York at Buffalo

Sex: All

Age: 18+

Code: NCT06222593

Phase1, Phase2, Recruiting

Lorlatinib Plus Local Consolidation Therapy In ALK Positive Advanced Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07415005

Phase2, Recruiting

Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)

for
Small Cell Lung Cancer
Location: New York NY, Fairfax VA, Tampa FL, Zion IL, Memphis TN,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07531095

Phase1, Recruiting

Low Intensity Focused Ultrasound for Chronic Pain: High Resolution Targeting of The Human Insula

for
Chronic Back Pain, Chronic Pain (Back / Neck)
Location: Washington D.C. DC
Sponsor: Washington D.C. Veterans Affairs Medical Center

Sex: All

Age: 21 - 70+

Code: NCT06906211

Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: New Haven CT, Brooklyn NY, New York NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06350097

Phase3, Recruiting

A Phase II Study for p16+ Oropharyngeal Cancer PerSonalized De-escalation Treatment at University of MIchigan (CuSToMIze)

for
Oropharyngeal Cancer, Squamous Cell Carcinoma of the Oropharynx
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT05894083

Phase2, Recruiting

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

for
Hearing Loss, Head and Neck Cancer
Location: Baltimore MD, Bethesda MD, Fairfax VA, Rochester NY,
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)

Sex: All

Age: 18 - 70+

Code: NCT04915183

Phase2, Recruiting

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

for
Carcinoma, Non-small-Cell Lung
Location: Boston MA, Hackensack NJ, New Brunswick NJ,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05498428

Phase2, Recruiting