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A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision

for
Skin Cancer, Cutaneous Squamous Cell Carcinoma (CSCC),
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06664151

Early_phase1, Recruiting

Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery

for
Clear Cell Renal Cell Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07037004

Phase2, Recruiting

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Peabody MA, Burlington MA, Livonia MI, Canton MI,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT07383441

Phase3, Recruiting

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC),
Location: Boston MA, Sarasota FL, Grand Rapids MI, Nashville TN,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06784193

Phase1, Recruiting

Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain

for
Back Pain, Neck Pain,
Location: Briarcliff Manor NY
Sponsor: Weintraub, Michael I., MD, FACP, FAAN

Sex: All

Age: 18 - 70+

Code: NCT00445133

Recruiting

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First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Non-small Cell Lung Cancer, EGFR Mutation,
Location: Nashville TN
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT05099172

Phase1, Phase2, Recruiting

A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Location: Omaha NE
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT05242965

Phase2, Recruiting

Tempus Small Cell Lung Cancer Observational Study (Sculptor)

for
Small Cell Lung Cancer
Location: Baltimore MD, York PA, Chapel Hill NC, Columbus OH,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05257551

Recruiting

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

for
Non-Hodgkin's Lymphoma, Diffuse Large B-Cell Lymphoma, DLBCL,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04002947

Phase2, Recruiting

Impact of COL7A1 Gene Therapy on SCC Recurrence in RDEB Skin

for
Squamous Cell Carcinoma
Location: Redwood City CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06731933

Phase2, Recruiting

MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)

for
Non-small Cell Lung Cancer
Location: Moncton, Chicoutimi, Montreal
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07431827

Phase3, Recruiting

A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

for
Extensive-stage Small-cell Lung Cancer
Location: Rock Hill SC, Jacksonville FL, Atlanta GA, Lexington KY,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07459634

Phase2, Recruiting

REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma

for
Metastatic Castration-Resistant Prostate Cancer (mCRPC),
Location: Tampa FL, Zion IL, Houston TX, Goodyear AZ, Duarte CA
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07594106

Phase1, Phase2, Recruiting

Precise Exercise Regimen for Cancer Care (PERCC): A Pilot Study

for
Stage II Lung Cancer, Lung Cancer, Non-small Cell Lung Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07412041

Recruiting

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Lake Success NY, Buffalo NY, Sarasota FL,
Sponsor: InduPro, Inc.

Sex: All

Age: 18+

Code: NCT07602842

Phase1, Phase2, Recruiting

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for
Solid Tumor, Non-Small Cell Lung Cancer, Head and Neck Cancer,
Location: Orange City FL, Clermont FL, Detroit MI, Atlanta GA,
Sponsor: Inhibrx Biosciences, Inc

Sex: All

Age: 18+

Code: NCT04198766

Phase1, Phase2, Recruiting

Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy

for
Cutaneous Squamous Cell Carcinoma, Skin Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07426484

Recruiting

DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer

for
Small-cell Lung Cancer, Small Cell Lung Cancer Extensive Stage
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07545954

Phase1, Recruiting

IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL

for
Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18+

Code: NCT06768905

Phase1, Phase2, Recruiting

Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Cardiotoxicity,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07761910

Phase2, Recruiting