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A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Farmington Hills MI, Atlanta GA, Farmington NM, Reno NV,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07541170

Phase3, Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for
Non-squamous Non-small Cell Lung Cancer
Location: Saint John, South Portland ME, West Haven CT,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06627647

Phase3, Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for
Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07285044

Phase2, Recruiting

Prospective Observational Cohort Study of Transplant and Cell Therapy Candidates and Recipients to Assess Social Determinants of Health

for
Transplant and Cell Therapy
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06431347

Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

for
Carcinoma, Non-Small Cell Lung
Location: Westbury NY, Fresh Meadows NY, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06868277

Phase3, Recruiting

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Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

for
Patients With Non-Small Cell Lung Cancer
Location: Rimouski, Worcester MA, Norwich CT, Patchogue NY,
Sponsor: OSE Immunotherapeutics

Sex: All

Age: 18+

Code: NCT06472245

Phase3, Recruiting

Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)

for
Small-cell Lung Cancer, Small Cell Lung Carcinoma,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07155200

Phase1, Phase2, Recruiting

A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Non-small Cell Lung Cancer, HER2 Mutation
Location: Montreal, Fort Lauderdale FL, Toronto, Pittsburgh PA,
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06452277

Phase3, Recruiting

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung
Location: Westbrook ME, Worcester MA, Hartford CT, New York NY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06890598

Phase3, Recruiting

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

for
Advanced or Metastatic Non-small Cell Lung Cancer
Location: Providence RI, Baltimore MD, Jacksonville FL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06996782

Phase1, Phase2, Recruiting

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

for
Non-small Cell Lung Cancer
Location: Philadelphia PA, Baltimore MD, Lexington KY, Fargo ND,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06731907

Phase2, Recruiting

MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach

for
Anal Squamous Cell Carcinoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06050707

Phase2, Recruiting

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

for
CLL/SLL, Waldenstrom Macroglobulinemia, Follicular Lymphoma,
Location: Durham NC, Columbus OH, Cincinnati OH,
Sponsor: Newave Pharmaceutical Inc

Sex: All

Age: 18+

Code: NCT04775745

Phase1, Recruiting

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

for
Hereditary Leiomyomatosis and Renal Cell Carcinoma,
Location: Bethesda MD, Columbus OH, Atlanta GA
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT04981509

Phase2, Recruiting

CIBMTR Research Database

for
Autologous Stem Cell Transplantation,
Location: Milwaukee WI, Minneapolis MN
Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All

Age: 0+

Code: NCT01166009

Recruiting

A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers

for
Oral Squamous Cell Carcinoma
Location: Miami FL, Cleveland OH, Chicago IL, Duarte CA
Sponsor: Privo Technologies

Sex: All

Age: 18 - 70+

Code: NCT05893888

Phase2, Phase3, Recruiting

Virtual Rehabilitation for Cancer Survivors

for
Breast Cancer, Stage 0, Colorectal Cancer Stage I,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05898789

Recruiting

Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer

for
Non-small Cell Lung Cancer
Location: Waterford CT, Guilford CT, Hamden CT, New Haven CT,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT04210492

Phase1, Phase2, Recruiting

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

for
Glioma, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT01772771

Recruiting

Talazoparib and Thoracic RT for ES-SCLC

for
Lung Cancer, Small-Cell Lung Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04170946

Phase1, Recruiting