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Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

for
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT01137643

Recruiting

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: New York NY, Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT06518057

Phase2, Recruiting

A Study of Mogamulizumab to Prevent Adult T-cell Leukemia/Lymphoma in People With HTLV-1

for
T-Cell Leukemia/Lymphoma, Adult, T-cell Leukemia/Lymphoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06698003

Phase2, Recruiting

Personalized NK Cell Therapy in CBT

for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 15 - 70+

Code: NCT02727803

Phase2, Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for
B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, New Haven CT, Valhalla NY, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 25

Code: NCT06395103

Phase1, Phase2, Recruiting

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Honokiol in Early-Stage Resectable Non-Small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT06566443

Phase1, Recruiting

Synapse 3D With Intravascular Indocyanine Green

for
Non-small Cell Lung Cancer, Primary Neoplasm
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT03953144

Phase1, Phase2, Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for
Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma,
Location: East Brunswick NJ, Philadelphia PA, York PA,
Sponsor: Guardant Health, Inc.

Sex: All

Age: 18+

Code: NCT05059444

Recruiting

Lurbinectedin in FET-Fused Tumors

for
Ewing Sarcoma, Desmoplastic Small Round Cell Tumor,
Location: Boston MA, New York NY, Philadelphia PA, Ann Arbor MI,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 10+

Code: NCT05918640

Phase1, Phase2, Recruiting

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for
Recurrent Lung Non-Small Cell Carcinoma,
Location: Brewer ME, Rockport ME, Belfast ME, Damariscotta ME,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06616584

Phase2, Phase3, Recruiting

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT04151940

Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer,
Location: Lake Success NY, Grand Rapids MI, Houston TX,
Sponsor: MacroGenics

Sex: All

Age: 18+

Code: NCT06242470

Phase1, Recruiting
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A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: New York NY, Philadelphia PA, Nashville TN, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase1, Recruiting

Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features

for
Non-small Cell Lung Cancer Stage III
Location: Washington D.C. DC, Charlottesville VA, St Louis MO
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT06449313

Phase2, Recruiting

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

for
Non-Small Cell Lung Cancer, Small Cell Lung Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT02146170

Recruiting

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for
Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme,
Location: Boston MA, New York NY, Washington D.C. DC, Fairfax VA,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06810544

Phase1, Phase2, Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung,
Location: Boston MA, Montreal, Baltimore MD, Ottawa, Toronto,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT06131840

Phase1, Recruiting

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Boston MA, Wynnewood PA, Bryn Mawr PA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03191149

Phase2, Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

for
Multiple Myeloma, Lymphoma, Non-Hodgkin,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02682667

Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for
Advanced Solid Tumor, Advanced Malignant Neoplasm,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: PMV Pharmaceuticals, Inc

Sex: All

Age: 12+

Code: NCT04585750

Phase1, Phase2, Recruiting