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A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

for
Prostate Cancer, Radiation Toxicity, Urinary Complication
Location: Rochester NY
Sponsor: University of Rochester

Sex: Male

Age: 18 - 70

Code: NCT05530655

Early_phase1, Recruiting

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 18+

Code: NCT06616155

Phase1, Phase2, Recruiting

PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer

for
Prostate Cancer, Prostate Adenocarcinoma,
Location: Miami FL
Sponsor: University of Miami

Sex: Male

Age: 18+

Code: NCT06392295

Phase2, Recruiting

Patient-Centered Communication of Life Expectancy Estimates in Genitourinary Malignancies

for
Prostate Cancer Stage I, Kidney Cancer Stage I,
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT03522155

Recruiting

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for
Prostate Cancer,
Location: Bala-Cynwyd PA, Towson MD, Myrtle Beach SC,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male

Age: 18+

Code: NCT04729114

Phase1, Recruiting

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Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

for
Ovarian Cancer, Pancreas Cancer, Urothelial Carcinoma,
Location: New York NY, Rochester NY, Atlanta GA, Denver CO,
Sponsor: Nammi Therapeutics Inc

Sex: All

Age: 18+

Code: NCT06582017

Phase1, Recruiting

Serial MRI Scans During Radiation Therapy

for
Glioblastoma, Esophageal Cancer, Radiotherapy,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04188535

Recruiting

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer

for
Prostate Cancer, Polygenic Risk Score
Location: Boston MA
Sponsor: Adam S. Kibel, MD

Sex: Male

Age: 40 - 69

Code: NCT06398639

Recruiting

Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)

for
Metastatic Prostate Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18 - 70+

Code: NCT05404139

Phase2, Recruiting

A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors

for
Advanced Cancer, Gastric Cancer, Breast Cancer,
Location: Winston-Salem NC, Birmingham AL, Scottsdale AZ,
Sponsor: Minneamrita Therapeutics LLC

Sex: All

Age: 18+

Code: NCT03129139

Phase1, Recruiting

ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer

for
Prostate Cancer
Location: San Diego CA
Sponsor: University of California, San Diego

Sex: Male

Age: 18+

Code: NCT06579417

Recruiting

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

for
Advanced Metastatic Castration-resistant Prostate Cancer,
Location: Sherbrooke, Montreal, Toronto, Hamilton, Vancouver
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06217822

Phase1, Recruiting

Prostate Active Surveillance Study

for
Prostatic Neoplasms
Location: Boston MA, Norfolk VA, Atlanta GA, Ann Arbor MI,
Sponsor: University of Washington

Sex: Male

Age: 21+

Code: NCT00756665

Recruiting

AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc

for
Breast Cancer Invasive, Prostate Cancer
Location: New York NY, Miami Beach FL
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT05351424

Recruiting

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

for
Overactive Bladder, Urinary Urgency Incontinence,
Location: New York NY, Bala-Cynwyd PA, Annapolis MD,
Sponsor: Axonics, Inc.

Sex: Male

Age: 18+

Code: NCT06511141

Recruiting

Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Efficacy Testing

for
Prostate Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Male

Age: 65+

Code: NCT06785441

Recruiting

A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: New Haven CT, New Brunswick NJ, Philadelphia PA,
Sponsor: Regeneron Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT05125016

Phase1, Phase2, Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

for
Cancer Risk, Cancer Predisposition Syndrome,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 0+

Code: NCT05463796

Recruiting

Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)

for
Prostate Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05043012

Recruiting

GU-01: Glycyrrhizin in Prostate Cancer

for
Prostate Cancer
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: Male

Age: 18+

Code: NCT06378346

Phase2, Recruiting