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Immunoregulatory Effect of Microparticle Delivered STING Agonist in the Control of Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS)

for
Relapse Remitting Multiple Sclerosis
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18 - 55

Code: NCT05705986

Recruiting

Hyperpolarized Carbon Metabolic Imaging in Multiple Sclerosis

for
Multiple Sclerosis, RRMS, Relapsing Remitting MS
Location: San Francisco CA
Sponsor: Ari Green

Sex: All

Age: 18+

Code: NCT07510607

Phase2, Recruiting

A Phase 2 Study of Radiotherapy-induced Immune Priming to Enhance Elranatamab (Elra) in Relapsed Refractory Multiple Myeloma (RRMM) With Extramedullary Disease (EMD) and Paramedullary Disease (PMD) "PRIME-EMD-PMD"

for
Phase 2, Radiotherapy-Induced Immune Priming, Elranatamab,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT07382739

Phase2, Recruiting
New

Inobrodib, Pomalidomide and Dexamethasone Versus Standard Available Therapy in Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma Refractory, Multiple Myeloma in Relapse
Location: Miami FL
Sponsor: CellCentric Ltd.

Sex: All

Age: 18+

Code: NCT07772024

Phase3, Recruiting
New

A Phase 1 Dose-escalation and Expansion Study of In Vivo BCMA-CAR T Cell Therapy (VV169) in Patients With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma Refractory, Multiple Myeloma in Relapse
Location: Rochester MN
Sponsor: Vyriad, Inc.

Sex: All

Age: 18+

Code: NCT07802717

Phase1, Recruiting

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Elranatamab in R/R Multiple Myeloma

for
Refractory Multiple Myeloma, Relapse Multiple Myeloma,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06138275

Phase2, Recruiting

Selinexor, Venetoclax, and Dexamethasone (XVenD) in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma

for
Relapsed and Refractory Multiple Myeloma
Location: Deerfield Beach FL, Miami FL, Coral Gables FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT05530421

Phase2, Recruiting

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

for
Relapsed Refractory Multiple Myeloma (RRMM)
Location: Durham NC
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT05730036

Phase3, Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

for
Relapsed or Refractory Multiple Myeloma,
Location: New York NY, Philadelphia PA, Charlotte NC, Houston TX,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05652335

Phase1, Recruiting

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

for
Relapsed/Refractory Multiple Myeloma
Location: Boston MA, Stony Brook NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05850234

Phase1, Phase2, Recruiting

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for
Relapsed or Refractory Multiple Myeloma (RRMM)
Location: Halifax, Boston MA, New York NY, Montreal,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06615479

Phase3, Recruiting

18F-Fluciclovine PET/CT in Multiple Myeloma

for
Multiple Myeloma, Newly Diagnosed Multiple Myeloma (NDMM),
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06103838

Phase2, Recruiting

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)

for
Relapsed/Refractory Multiple Myeloma
Location: Boston MA, The Bronx NY, Chapel Hill NC, Atlanta GA,
Sponsor: Ichnos Sciences SA

Sex: All

Age: 18+

Code: NCT05862012

Phase1, Recruiting

Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple Myeloma

for
Relapsed Cancer, Refractory Multiple Myeloma, Multiple Myeloma
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05922501

Phase2, Recruiting

PRO and Wearable Data Insights From Individuals With R/R Multiple Myeloma

for
Multiple Myeloma, Relapsed Hematologic Malignancy
Location: Seattle WA
Sponsor: Pack Health

Sex: All

Age: 18+

Code: NCT05956457

Recruiting

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

for
Relapsed or Refractory Multiple Myeloma
Location: Boston MA, New York NY, Hillsborough NC,
Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT06375044

Phase1, Recruiting

Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse

for
Multiple Myeloma in Relapse
Location: New York NY
Sponsor: Larysa Sanchez

Sex: All

Age: 70+

Code: NCT06827860

Phase2, Recruiting

Early Palliative Care for Patients With Multiple Myeloma and Aggressive Lymphoma

for
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06485076

Recruiting

A Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory Multiple Myeloma

for
Multiple Myeloma (MM), Multiple Myeloma Refractory,
Location: Columbia MD, Nashville TN, Denver CO, Las Vegas NV,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 18+

Code: NCT07637578

Phase2, Recruiting

Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS)

for
Relapsed/Refractory Multiple Myeloma (RRMM)
Location: Bethesda MD, Baton Rouge LA, Tacoma WA, Los Angeles CA
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07609940

Recruiting