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Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

for
Multiple Myeloma, Relapse Multiple Myeloma
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT05789303

Phase2, Recruiting

Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas

for
Primary Central Nervous System Lymphoma,
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05681195

Phase2, Recruiting

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

for
Pediatric Sarcoma, Refractory, Pediatric Sarcoma, Relapsed
Location: The Bronx NY, Philadelphia PA, Durham NC,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 2 - 40

Code: NCT05634369

Phase1, Phase2, Recruiting

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

for
Relapsed/Refractory Primary Central Nervous System Lymphoma
Location: Boston MA, Providence RI, New Haven CT, New York NY,
Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT07104032

Phase3, Recruiting

A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)

for
Primary Central Nervous System Lymphoma (PCNSL),
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07082868

Phase1, Recruiting

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Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

for
Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS,
Location: Baltimore MD, Washington D.C. DC
Sponsor: Catherine Bollard

Sex: All

Age: 0 - 70+

Code: NCT02203903

Phase1, Recruiting

Pembrolizumab, Ibrutinib and Rituximab in PCNSL

for
Primary Central Nervous System Lymphoma, Recurrent Cancer,
Location: Boston MA, New York NY
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04421560

Phase1, Phase2, Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

for
Recurrent Glioblastoma,
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT07416188

Phase1, Phase2, Recruiting

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for
Relapsed Hematologic Malignancy,
Location: Boston MA, New York NY, Durham NC, Buffalo NY,
Sponsor: Curis, Inc.

Sex: All

Age: 18+

Code: NCT03328078

Phase1, Phase2, Recruiting

DALY II USA/ MB-CART2019.1 for DLBCL

for
Refractory Diffuse Large B Cell Lymphoma (DLBCL),
Location: Boston MA, New Haven CT, New York NY, Baltimore MD,
Sponsor: Miltenyi Biomedicine GmbH

Sex: All

Age: 18+

Code: NCT04792489

Phase2, Recruiting

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

for
Non Hodgkin Lymphoma,
Location: Boston MA, New Haven CT, Durham NC, Chicago IL,
Sponsor: Miltenyi Biomedicine GmbH

Sex: All

Age: 18+

Code: NCT06116110

Recruiting

ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS

for
Relapsing Remitting Multiple Sclerosis (RRMS)
Location: St. John's, Halifax, Montreal, Sherbrooke, Quebec,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06733922

Recruiting

Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

for
Relapsing-remitting Multiple Sclerosis,
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Female

Age: 18 - 55

Code: NCT01466114

Phase2, Recruiting

A Safety Study of Combination Treatment With Avonex and Zocor in Relapsing Remitting Multiple Sclerosis

for
Relapsing Remitting Multiple Sclerosis
Location: Birmingham AL
Sponsor: Alabama Neurology Associates, PC

Sex: All

Age: 18 - 55

Code: NCT00242268

Phase3, Recruiting

A Safety Study of Combination Treatment With Avonex and Placebo-Controlled Dosing of Topamax in Relapsing-Remitting Multiple Sclerosis

for
Multiple Sclerosis
Location: Philadelphia PA
Sponsor: Multiple Sclerosis Institute

Sex: All

Age: 18 - 55

Code: NCT00217295

Phase2, Recruiting

Endpoint Calibration for a Phase 2 Study of Lisinopril in Multiple Sclerosis

for
Multiple Sclerosis, Relapsing-Remitting
Location: New York NY
Sponsor: Transparency Life Sciences

Sex: All

Age: 18 - 64

Code: NCT02369926

Phase2, Recruiting

Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma

for
Refractory Multiple Myeloma, Relapsed Multiple Myeloma
Location: Miami FL
Sponsor: Benjamin T Diamond, MD

Sex: All

Age: 18 - 70+

Code: NCT05896228

Phase2, Recruiting