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Active & Responsive

Cognitive Function in Rett Syndrome During Trofinetide Treatment

for
Rett Syndrome
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 18 - 70+

Code: NCT06705816

Recruiting
New

A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome

for
Rett Syndrome
Location: Toronto
Sponsor: Holland Bloorview Kids Rehabilitation Hospital

Sex: Female

Age: 2 - 21

Code: NCT04041713

Phase2, Recruiting

Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome

for
Rett Syndrome
Location: Washington DC
Sponsor: Georgetown University

Sex: All

Age: 4 - 60

Code: NCT05012475

Recruiting

The Diagnostic Experience of Male Rett Syndrome

for
Rett Syndrome, RTT
Location: Aurora CO
Sponsor: Children's Hospital Colorado

Sex: Male

Age: 0 - 70+

Code: NCT06346106

Recruiting

Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome

for
Rett Syndrome
Location: Baltimore MD
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All

Age: 1 - 15

Code: NCT00069550

Phase3, Recruiting

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Neurophysiologic Biomarkers in Rett Syndrome

for
Rett Syndrome, RTT, Rett Syndrome, Atypical
Location: Brookline MA, Philadelphia PA, Nashville TN, Houston TX,
Sponsor: Children's Hospital of Philadelphia

Sex: Female

Age: 1 - 18

Code: NCT05932589

Recruiting

Treatment of Mitochondrial Dysfunction in Rett Syndrome With Triheptanoin

for
Rett Syndrome
Location: Norcross GA
Sponsor: Center for Rare Neurological Diseases, Norcross, GA

Sex: Female

Age: 2+

Code: NCT02696044

Phase2, Recruiting

A Phase 3 Study of Fenfluramine Hydrochloride in Rett Syndrome

for
Rett Syndrome
Location: Orlando FL, Atlanta GA, Little Rock AR, Houston TX,
Sponsor: UCB BIOSCIENCES, Inc.

Sex: All

Age: 5 - 35

Code: NCT07503444

Phase3, Recruiting

Auditory EEG and Behavioral Assessments in Individuals With Rett Syndrome

for
Rett Syndrome
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 2+

Code: NCT07569445

Recruiting

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

for
Neurodevelopmental Disorders,
Location: The Woodlands TX
Sponsor: Healing Hope International

Sex: All

Age: 4 - 12

Code: NCT07493096

Recruiting

Rett Syndrome Registry

for
Rett Syndrome, Rett Syndrome, Atypical, Genetic Disease,
Location: Boston MA, Philadelphia PA, Baltimore MD,
Sponsor: International Rett Syndrome Foundation

Sex: All

Age: 0 - 70+

Code: NCT05432349

Recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

for
Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Location: Boston MA, Philadelphia PA, Baltimore MD, Nashville TN,
Sponsor: Ionis Pharmaceuticals, Inc.

Sex: Male

Age: 2 - 65

Code: NCT06430385

Phase1, Phase2, Recruiting

To Investigate the Efficacy of Treatment With Oral NA-921 (Bionetide) Versus Placebo in Females With Rett Syndrome

for
Rett Syndrome
Location: Boston MA, The Bronx NY, Baltimore MD, Tampa FL,
Sponsor: Biomed Industries, Inc.

Sex: Female

Age: 5 - 20

Code: NCT06840496

Phase3, Recruiting

The Rett Syndrome Global Registry

for
Rett Syndrome
Location: Trumbull CT
Sponsor: Rett Syndrome Research Trust

Sex: All

Age: 0+

Code: NCT04900493

Recruiting