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A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

for
Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer,
Location: Austin TX, San Antonio TX, Scottsdale AZ
Sponsor: OncoResponse, Inc.

Sex: All

Age: 18+

Code: NCT05094804

Phase1, Phase2, Recruiting

SNV4818 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, Philadelphia PA, Ottawa, Toronto,
Sponsor: Pikavation Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06736704

Phase1, Phase2, Recruiting

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

for
Solid Tumors
Location: Cleveland OH, Nashville TN, St Louis MO, Houston TX,
Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All

Age: 18+

Code: NCT06386146

Phase1, Phase2, Recruiting

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Fairfax VA, Jacksonville FL, Tampa FL, Sarasota FL,
Sponsor: Vividion Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05954312

Phase1, Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase1, Phase2, Recruiting

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A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

for
Hematological Malignancy, Solid Tumor Malignancy
Location: Baltimore MD, Charlotte NC, Cincinnati OH, Seattle WA
Sponsor: Century Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05768269

Recruiting

X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

for
Advanced Solid Tumor Cancer
Location: Washington D.C. DC, Durham NC, Charlotte NC,
Sponsor: Immunolight, LLC

Sex: All

Age: 18+

Code: NCT04389281

Phase1, Recruiting

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for
Locally Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Scarborough ME, Boston MA, Montreal, Philadelphia PA,
Sponsor: Turning Point Therapeutics, Inc.

Sex: All

Age: 0 - 25

Code: NCT04094610

Phase1, Phase2, Recruiting

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for
Solid Tumor
Location: New York NY, Montreal, Chapel Hill NC, Miami FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT04939610

Phase1, Phase2, Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Antitumor Activity of ALK202 in Participants with Advanced Solid Tumors

for
Advanced Cancer, Advanced Solid Tumor
Location: Fairfax VA, Margate FL
Sponsor: Shanghai Allink Biotherapeutics Co., Ltd.

Sex: All

Age: 18 - 70+

Code: NCT06707610

Phase1, Recruiting

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

for
Melanoma, Lymphoma, Solid Tumor, Classical Hodgkin Lymphoma,
Location: Boston MA, New York NY, Chicago IL, Fargo ND,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 17

Code: NCT02332668

Phase1, Phase2, Recruiting

A Dose Escalation and Expansion Study of GIGA-564 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

for
Advanced or Metastatic Solid Tumor Malignancies
Location: Bethesda MD
Sponsor: GigaGen, Inc.

Sex: All

Age: 18+

Code: NCT06258304

Phase1, Recruiting

First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors

for
Select Advanced Solid Tumors
Location: Philadelphia PA, Miami FL, Ann Arbor MI, Portland OR
Sponsor: CDR-Life AG

Sex: All

Age: 18+

Code: NCT06402201

Phase1, Recruiting

Home-Based Symptom Monitoring: Its Impact on Cancer Care Team Behaviors and Patient Outcomes

for
Cancer, Solid Tumor, Hematologic Malignancy
Location: Indianapolis IN, Martinsville IN
Sponsor: Community Cancer Care

Sex: All

Age: 18+

Code: NCT00300001

Recruiting

High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis

for
Solid Tumor
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT05301101

Recruiting

Pan-tumor MRD Study

for
Muscle Invasive Bladder Urothelial Carcinoma, Esophageal Cancer,
Location: Maumee OH, San Diego CA
Sponsor: Flatiron Health

Sex: All

Age: 18+

Code: NCT06605404

Recruiting

Universal Germline Testing in the Community

for
Cancer, Solid Tumor, Solid Tumor, Adult
Location: Rock Hill SC
Sponsor: Invitae Corporation

Sex: All

Age: 18+

Code: NCT05416710

Recruiting

First in Human Study of UCT-03-008 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Dallas TX, Los Angeles CA
Sponsor: 1200 Pharma, LLC

Sex: All

Age: 18+

Code: NCT05103046

Phase1, Recruiting

SW-682 in Advanced Solid Tumors

for
Advanced Solid Tumor, Mesothelioma, Malignant
Location: Cleveland OH, Houston TX, Dallas TX, Scottsdale AZ,
Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany

Sex: All

Age: 18+

Code: NCT06251310

Phase1, Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for
Solid Tumors With HRAS Alterations,
Location: Boston MA, New Brunswick NJ, Pittsburgh PA,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06026410

Phase1, Recruiting