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Phase I Study VG2025 as a Single Agent and in Combination Therapy With Nivolumab in Subjects With Advanced Malignant Solid Tumors

for
Solid Tumor
Location: Houston TX, Gilbert AZ
Sponsor: Virogin Biotech Canada Ltd

Sex: All

Age: 18+

Code: NCT05266612

Phase1, Recruiting

A Study to Investigate Fadraciclib (CYC065), in Subjects With Advanced Solid Tumors and Lymphoma

for
Solid Tumor, Adult, Lymphoma
Location: Houston TX, Duarte CA
Sponsor: Cyclacel Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT04983810

Phase1, Phase2, Recruiting

A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS

for
Advanced Solid Tumors
Location: Miami Beach FL, St. Petersburg FL, New Orleans LA
Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Sex: All

Age: 18+

Code: NCT05277168

Phase1, Phase2, Recruiting

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

for
Malignant Head and Neck Neoplasm, Malignant Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT01365169

Recruiting

Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors

for
Solid Tumors, Adult
Location: Irving TX, San Antonio TX
Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Sex: All

Age: 18+

Code: NCT06504368

Phase1, Recruiting

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A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

for
Advanced/Metastatic Solid Tumors, Colorectal Cancer,
Location: Boston MA, New York NY, Philadelphia PA, Syracuse NY,
Sponsor: Merus B.V.

Sex: All

Age: 18+

Code: NCT03526835

Phase1, Phase2, Recruiting

Study of MTB-9655, an Inhibitor of ACSS2, in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Nashville TN
Sponsor: MetaboMed Inc

Sex: All

Age: 18+

Code: NCT04990739

Phase1, Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors, HNSCC, SCLC, NSCLC,
Location: Boston MA, New York NY, New Haven CT, Miami FL, Toronto,
Sponsor: Tubulis GmbH

Sex: All

Age: 18+

Code: NCT06657222

Phase1, Phase2, Recruiting

Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors

for
Solid Tumor
Location: Grand Rapids MI, Scottsdale AZ
Sponsor: Qualigen Theraputics, Inc.

Sex: All

Age: 18+

Code: NCT06086522

Phase1, Recruiting

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

for
Advanced or Metastatic Solid Tumors, Non Small Cell Lung Cancer,
Location: Boston MA, New Haven CT, Fairfax VA, Nashville TN,
Sponsor: Incendia Therapeutics

Sex: All

Age: 18+

Code: NCT05753722

Phase1, Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

for
Advanced Solid Tumor, Metastatic Cancer, Cutaneous Melanoma,
Location: Morristown NJ, Miami FL, Huntersville NC,
Sponsor: Aulos Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05267626

Phase1, Phase2, Recruiting

COAST Therapy in Advanced Solid Tumors and Prostate Cancer

for
Prostate Cancer Recurrent, Solid Tumor, Adult
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05036226

Phase1, Phase2, Recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

for
Melanoma Stage IV, Solid Tumor
Location: Boston MA, New York NY, Richmond VA, Cincinnati OH,
Sponsor: Georgiamune Inc

Sex: All

Age: 18+

Code: NCT06425926

Phase1, Phase2, Recruiting

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

for
NSCLC (Non-small Cell Lung Cancer), Solid Tumor
Location: Fairfax VA
Sponsor: Yuhan Corporation

Sex: All

Age: 18+

Code: NCT06616766

Phase1, Phase2, Recruiting

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

for
Advanced Solid Tumor, Cutaneous T-cell Lymphoma (CTCL)
Location: Huntersville NC
Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT05569057

Phase1, Recruiting

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

for
Solid Tumor, Adult, Carcinoma, Ovarian Epithelial,
Location: Silver Spring MD, Detroit MI, Houston TX, Dallas TX
Sponsor: Bio-Path Holdings, Inc.

Sex: All

Age: 18+

Code: NCT04196257

Phase1, Recruiting

A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention

for
Solid Tumor, Adult
Location: Chico CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06436157

Recruiting

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

for
Advanced Solid Tumors, Breast Cancer Recurrent, Ovarian Cancer,
Location: New York NY, Fairfax VA, Sarasota FL, Detroit MI,
Sponsor: Accent Therapeutics

Sex: All

Age: 18+

Code: NCT06799065

Phase1, Recruiting

A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

for
Advanced Solid Tumor, Metastatic Breast Cancer
Location: Lake Mary FL, Sarasota FL, Nashville TN, Houston TX
Sponsor: Edgewood Oncology Inc.

Sex: All

Age: 18+

Code: NCT04872166

Phase1, Recruiting

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

for
Lung Cancer, Non-small Cell, Lung Cancer Metastatic,
Location: Weston FL, Canton OH, Cleveland OH, Detroit MI,
Sponsor: Krystal Biotech, Inc.

Sex: All

Age: 18+

Code: NCT06228326

Phase1, Phase2, Recruiting