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Ex Vivo Expansion (ACT-X)

for
Solid Tumor, Healthy, Malignant Solid Neoplasm
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07137312

Recruiting

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for
Advanced or Metastatic Solid Tumors
Location: New Haven CT, Philadelphia PA, Baltimore MD, Fairfax VA,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07205718

Phase1, Phase2, Recruiting

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

for
Advanced/Metastatic Solid Tumors
Location: Fairfax VA, Pittsburgh PA, Ann Arbor MI, Houston TX,
Sponsor: DualityBio Inc.

Sex: All

Age: 18+

Code: NCT07141706

Phase1, Recruiting

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

for
Solid Tumors, Advanced Solid Tumor
Location: Fairfax VA, Houston TX, San Antonio TX
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07181681

Phase1, Recruiting

A Study to Evaluate the Safety and Antitumor Activity of GS-1206 in Adults With Solid Tumors

for
Solid Tumor
Location: Grand Rapids MI, Texas City TX, San Antonio TX
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT07703878

Phase1, Recruiting

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A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

for
Advanced Solid Tumors
Location: Grand Rapids MI, San Antonio TX, West Valley City UT
Sponsor: ModernaTX, Inc.

Sex: All

Age: 18+

Code: NCT06880549

Phase1, Recruiting

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for
Solid Tumor, Non-Small Cell Lung Cancer, Head and Neck Cancer,
Location: Orange City FL, Clermont FL, Detroit MI, Atlanta GA,
Sponsor: Inhibrx Biosciences, Inc

Sex: All

Age: 18+

Code: NCT04198766

Phase1, Phase2, Recruiting

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Lake Success NY, Buffalo NY, Sarasota FL,
Sponsor: InduPro, Inc.

Sex: All

Age: 18+

Code: NCT07602842

Phase1, Phase2, Recruiting

SLR-108 PET Imaging in Subjects With Metastatic Solid Tumors

for
Metastatic Solid Tumors
Location: Newport Beach CA
Sponsor: Solve Therapeutics

Sex: All

Age: 18+

Code: NCT07728942

Phase1, Recruiting

A Study to Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Lake Success NY
Sponsor: LigaChem Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07460375

Phase1, Phase2, Recruiting

Study of GS-2426 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: New York NY, East Brunswick NJ, Grand Rapids MI,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT07601243

Phase1, Recruiting

A Study of Safety, Tolerability and Preliminary Efficacy of NTS071 in Subjects With Advanced Solid Tumors Harboring a TP53 Y220C Mutation

for
Advanced Solid Tumors
Location: San Antonio TX
Sponsor: Nutshell Therapeutics (Shanghai) Co., LTD.

Sex: All

Age: 18+

Code: NCT07060989

Phase1, Phase2, Recruiting

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

for
Gastric Cancer, Gastric Adenocarcinoma,
Location: Fairfax VA
Sponsor: BigHat Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07529808

Phase1, Phase2, Recruiting

A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Providence RI, Fairfax VA, Toronto, Sarasota FL,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT05765851

Phase1, Recruiting

FORTRAS: A Study of MSK-TCR5 in People With Solid Tumor Cancers

for
Solid Tumor, Solid Carcinoma, Advanced Solid Tumor,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07638371

Phase1, Recruiting

A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations

for
Advanced Solid Tumors With MAPK Pathway Mutations
Location: Detroit MI, Nashville TN, Houston TX
Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All

Age: 18+

Code: NCT05886920

Phase1, Phase2, Recruiting

Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Advanced Solid Tumor, Metastatic Solid Tumor
Location: San Antonio TX
Sponsor: Lei Zheng

Sex: All

Age: 18+

Code: NCT07086768

Phase1, Recruiting

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

for
Solid Tumor Malignancies, Testicular Cancer,
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 18+

Code: NCT07407582

Phase1, Phase2, Recruiting

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

for
PIK3CA Mutations, Advanced Solid Tumors, Adult,
Location: Boston MA, East Brunswick NJ, Fairfax VA, Tampa FL,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07383506

Phase1, Recruiting

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

for
Advanced Solid Tumor, Non-Small Cell Lung Cancer,
Location: Fairfax VA, Tampa FL, Sarasota FL
Sponsor: Blueprint Medicines Corporation

Sex: All

Age: 18+

Code: NCT07629960

Phase1, Phase2, Recruiting