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Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma,
Location: Toronto, Dallas TX, San Antonio TX
Sponsor: Auricula Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07148128

Phase1, Phase2, Recruiting

Phase II Biomarker Study of BND-22 in Combination With Cemiplimab in Solid Tumors

for
Solid Tumors
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06651593

Phase2, Recruiting

PET [89Zr]DFO-starPEG in Solid Tumors

for
Solid Tumor, Solid Carcinoma, Soft Tissue Lesion
Location: San Francisco CA
Sponsor: Robert Flavell, MD, PhD

Sex: All

Age: 18+

Code: NCT06894745

Phase1, Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for
Metastatic Solid Tumor, Recurrent Solid Tumor,
Location: Boston MA, New York NY, Cleveland OH, Grand Rapids MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06465069

Phase1, Recruiting

A Study of HS-20110 in Participants With Advanced Solid Tumors

for
Solid Tumors
Location: Fairfax VA, Tamarac FL, Huntersville NC, Fort Wayne IN,
Sponsor: Hansoh BioMedical R&D Company

Sex: All

Age: 18+

Code: NCT06892379

Phase1, Recruiting

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A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)

for
Advanced Solid Tumors, Malignant Neoplasm
Location: Hackensack NJ, Richmond VA, Miami FL, Birmingham AL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06818643

Phase1, Phase2, Recruiting

A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid Tumors

for
Solid Tumors
Location: New Brunswick NJ, Washington D.C. DC, Orlando FL,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT07123103

Phase1, Recruiting

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Advanced Breast Cancer
Location: Boston MA, New Haven CT, Fairfax VA, Huntersville NC,
Sponsor: Ensem Therapeutics

Sex: All

Age: 18+

Code: NCT06993844

Phase1, Phase2, Recruiting

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

for
Solid Tumor Cancer, Locally Advanced, Metastatic Solid Tumors,
Location: Washington D.C. DC, Sarasota FL, Atlanta GA, Houston TX,
Sponsor: Avenzo Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07038343

Phase1, Phase2, Recruiting

PumaRx Registry Trial

for
Solid Tumors
Location: Burlington VT, Coral Gables FL, Pittsburgh PA
Sponsor: RenovoRx

Sex: All

Age: 18+

Code: NCT06805461

Recruiting

Implementation of an Oral Chemotherapy Adherence Intervention

for
Solid Tumor, Hematologic Malignancy
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 21+

Code: NCT06989489

Recruiting

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Raleigh NC, Tampa FL, Detroit MI, St Louis MO,
Sponsor: MOMA Therapeutics

Sex: All

Age: 18+

Code: NCT06974110

Phase1, Recruiting

Intravital Microscopy in Human Solid Tumors

for
Solid Tumor, Adult, Clinical Stage IV Gastric Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03823144

Recruiting

A Phase I Safety and Pharmacokinetic Study of Gamitrinib Administered Intravenously to Patients With Advanced Cancer

for
Lymphoma, Advanced Solid Tumor
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT04827810

Phase1, Recruiting

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Hackensack NJ, Fairfax VA, Madison WI, Houston TX
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06598800

Phase1, Recruiting

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

for
Advanced Solid Tumor, Advanced Breast Cancer,
Location: Boston MA, Lebanon NH, New Hyde Park NY, New York NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06997029

Phase1, Recruiting

Study of AUBE00 in Patients With Solid Tumors

for
Solid Tumors
Location: Grand Rapids MI, Houston TX
Sponsor: Chugai Pharmaceutical

Sex: All

Age: 18+

Code: NCT07030959

Phase1, Recruiting

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

for
Locally Advanced/Metastatic Solid Tumors
Location: New Haven CT, Indianapolis IN, Nashville TN, Denver CO,
Sponsor: InSilico Medicine Hong Kong Limited

Sex: All

Age: 18+

Code: NCT06414460

Phase1, Phase2, Recruiting

Imaging of Solid Tumors Using 18F-TRX

for
Solid Tumor, Solid Carcinoma,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT06942104

Phase1, Recruiting

A Study of ZL-1310 in Participants With Selected Solid Tumors

for
Solid Tumors
Location: New York NY, Philadelphia PA, Norfolk VA, Fairfax VA,
Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All

Age: 18+

Code: NCT06885281

Phase1, Phase2, Recruiting