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A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor
Location: Philadelphia PA, Celebration FL, Sioux Falls SD,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06803680

Phase1, Recruiting

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for
Pancreatic Ductal Adenocarcinoma, Non Small Cell Lung Cancer,
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07020221

Phase1, Phase2, Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment

for
Advanced Solid Tumors, Hematologic Malignancies
Location: Canton OH, Detroit MI, Chicago IL
Sponsor: Acrotech Biopharma Inc.

Sex: All

Age: 18+

Code: NCT07036133

Phase1, Recruiting

A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

for
Advanced Stage Solid Tumors
Location: New York NY, Fairfax VA, Sarasota FL, Nashville TN
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07107230

Phase1, Recruiting

Study of ISM6331 in Participants With Advanced/Metastatic Mesothelioma or Other Advanced Solid Tumors

for
Malignant Mesothelioma, Metastatic Malignant Solid Tumor,
Location: Philadelphia PA, Cleveland OH, Nashville TN, Denver CO,
Sponsor: InSilico Medicine Hong Kong Limited

Sex: All

Age: 18+

Code: NCT06566079

Phase1, Phase2, Recruiting

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A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors

for
Recurrent or Metastatic Solid Tumors
Location: Charlotte NC, Maumee OH, Atlanta GA, Nashville TN,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT07015697

Phase1, Recruiting

A Clinical Trial to Evaluate the Safety, Tolerability and Clinical Efficacy of M3T01 Monotherapy and in Combination With Pembrolizumab and Other Systemic Therapies

for
Advanced Solid Tumors
Location: Portland OR
Sponsor: Providence Health & Services

Sex: All

Age: 18+

Code: NCT06719362

Phase1, Recruiting

A Study of a Distress Screening and Referral Program in People With Recently Diagnosed Cancer

for
Solid Tumor Cancer
Location: Richmond Hill NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07117461

Recruiting

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for
HR+ Breast Cancer, Triple Negative Breast Cancer (TNBC),
Location: Boston MA, New Haven CT, Fairfax VA, Morgantown WV,
Sponsor: NiKang Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07029399

Phase1, Recruiting

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

for
Cancer, Solid Tumor, Adult, Cancer Metastatic, Solid Carcinoma,
Location: San Antonio TX
Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

Sex: All

Age: 18+

Code: NCT04443088

Phase1, Recruiting

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

for
Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer,
Location: Boston MA, Goodyear AZ, Duarte CA
Sponsor: I-Mab Biopharma US Limited

Sex: All

Age: 18+

Code: NCT07432295

Phase2, Recruiting

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

for
Locally Advanced / Metastatic Solid Tumors
Location: New York NY, Washington D.C. DC, Pittsburgh PA,
Sponsor: Crescent Biopharma, Inc.

Sex: All

Age: 18+

Code: NCT07335497

Phase1, Phase2, Recruiting

An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors

for
Advanced Malignant Solid Tumor
Location: Grand Rapids MI
Sponsor: Repertoire Immune Medicines

Sex: All

Age: 18+

Code: NCT07293754

Phase1, Phase2, Recruiting

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

for
Mesothelioma, Non Small Cell Lung Cancer,
Location: Brookline MA, Port Jefferson Station NY, Mineola NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT05245500

Phase1, Recruiting

A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors

for
Solid Tumor, Adult, Advanced Solid Tumor, Advanced Cancer,
Location: Boston MA, New York NY, Houston TX, San Antonio TX,
Sponsor: Monopteros Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT04859777

Phase1, Recruiting

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Patients With Solid Tumors

for
Metastatic Solid Tumor, Locally Advanced Solid Tumor
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT06358677

Phase2, Recruiting

RAPA-201 Therapy of Solid Tumors

for
Solid Tumor, Small Cell and Non-small Cell Lung Cancer,
Location: Hackensack NJ
Sponsor: Rapa Therapeutics LLC

Sex: All

Age: 18+

Code: NCT05144698

Phase1, Phase2, Recruiting

Safety of PUR001 Monotherapy in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Houston TX
Sponsor: Purinomia Biotech, Inc.

Sex: All

Age: 18+

Code: NCT05234853

Phase1, Recruiting

DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic Solid Tumors
Location: New Haven CT, The Bronx NY, Baltimore MD, Miami FL,
Sponsor: DynamiCure Biotechnology

Sex: All

Age: 18+

Code: NCT05785754

Phase1, Recruiting

A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

for
Advanced Solid Tumors That Are MTAP Deficient
Location: Providence RI, New Haven CT, Baltimore MD, Fairfax VA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06130553

Phase1, Phase2, Recruiting