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GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor, Cervical Cancer,
Location: New York NY, Huntersville NC
Sponsor: GI Innovation, Inc.

Sex: All

Age: 18+

Code: NCT04977453

Phase1, Phase2, Recruiting

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

for
Breast Cancer, Colorectal Cancer, Pancreas Cancer,
Location: Kingston, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05403177

Recruiting

Niraparib and Dostarlimab in HRD Solid Tumors

for
Homologous Recombination Deficient Solid Tumors
Location: Germantown TN
Sponsor: West Cancer Center

Sex: All

Age: 0 - 70+

Code: NCT04983745

Phase2, Recruiting

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Melanoma, HNSCC, Sarcoma, Squamous Cell Carcinoma,
Location: Boston MA, Fairfax VA, Pittsburgh PA, Dallas TX
Sponsor: ImmVira Pharma Co. Ltd

Sex: All

Age: 18+

Code: NCT04370587

Phase1, Phase2, Recruiting

EIS-12656 as Single Agent and in Combination in Patients With Specified Solid Tumors

for
Advanced Solid Tumor, Homologous Recombination Deficiency,
Location: Houston TX
Sponsor: Eisbach Bio GmbH

Sex: All

Age: 18+

Code: NCT06525298

Phase1, Phase2, Recruiting

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for
Cancer Harboring BRAF Alterations, HGG, LGG, Solid Tumors
Location: Boston MA, Providence RI, Norwalk CT, New York NY,
Sponsor: Fore Biotherapeutics

Sex: All

Age: 8+

Code: NCT05503797

Phase2, Recruiting

Phase 1, First in Human, Open-Label, Dose-Escalation Study of 609A

for
Solid Tumors
Location: San Antonio TX
Sponsor: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

Sex: All

Age: 18+

Code: NCT03950297

Phase1, Recruiting

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

for
Tumor, Solid, Tumor, Advanced Solid Tumor
Location: San Antonio TX, West Valley City UT
Sponsor: Aadi Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05661461

Phase1, Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

for
Cancer, Advanced Cancer, Locally Advanced Carcinoma,
Location: Fairfax VA, Sarasota FL, Nashville TN, St Louis MO,
Sponsor: Angiex, Inc.

Sex: All

Age: 18+

Code: NCT06440005

Phase1, Recruiting

Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors

for
Unspecified Adult Solid Tumor, Protocol Specific
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT02215928

Recruiting

A Study in Patients With Advanced Cancers

for
Advanced Cancer, Advanced Solid Tumor, Cancer, Oncology
Location: Fairfax VA, Houston TX, Austin TX
Sponsor: BiOneCure Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT05320588

Phase1, Phase2, Recruiting

LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers

for
Solid Tumor
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04665388

Recruiting

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, Philadelphia PA, Fairfax VA, Houston TX,
Sponsor: Tagworks Pharmaceuticals BV

Sex: All

Age: 18+

Code: NCT06959706

Phase1, Recruiting

A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors

for
Solid Tumor, HNSCC, RCC, CRC
Location: Jacksonville FL, Rochester MN, Scottsdale AZ,
Sponsor: SparX Biotech(Jiangsu) Co., Ltd.

Sex: All

Age: 18+

Code: NCT06259552

Phase1, Recruiting

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

for
Advanced Solid Tumor, Advanced Breast Cancer,
Location: Durham NC, Columbus OH, Nashville TN, Denver CO,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06120283

Phase1, Recruiting

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

for
Wilms Tumor, Rhabdoid Tumor,
Location: Boston MA, Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 1+

Code: NCT05985161

Phase2, Recruiting

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Lake Success NY, Hackensack NJ, Charlotte NC,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06697197

Phase1, Phase2, Recruiting

Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic Solid Tumors
Location: Tampa FL, Cincinnati OH, Grand Rapids MI,
Sponsor: Hanmi Pharmaceutical Company Limited

Sex: All

Age: 18+

Code: NCT06234397

Phase1, Recruiting

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New Haven CT, Madison WI, Houston TX, Seattle WA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06625593

Phase1, Recruiting

Study of ON 123300 in Patients With Advanced Cancer

for
Solid Tumors, Adult
Location: Greenville SC, Grand Rapids MI, Dallas TX
Sponsor: Traws Pharma, Inc.

Sex: All

Age: 18+

Code: NCT04739293

Phase1, Recruiting