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Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

for
Metastatic Bladder Urothelial Carcinoma,
Location: Chicago IL, Orland Park IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT06630416

Phase2, Recruiting

Genetic Testing for the Prevention of Cancer in American Indian Communities (JUNIPER Trial)

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06569316

Recruiting

Transportation for Cancer Care Navigation Tool for Reducing Travel Barriers Among Patients With Solid Tumors Receiving Radiation Therapy

for
Malignant Solid Neoplasm
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06541158

Recruiting

AOH1996 for the Treatment of Refractory Solid Tumors

for
Refractory Malignant Solid Neoplasm, Osteosarcoma,
Location: Duarte CA, Long Beach CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05227326

Phase1, Recruiting

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

for
Malignant Brain Neoplasm, Malignant Solid Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT06788886

Recruiting

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Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05178472

Recruiting

Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

for
Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04693468

Phase1, Recruiting

Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06640010

Recruiting

Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning

for
Locally Advanced Malignant Solid Neoplasm,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT04515810

Recruiting

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for
Advanced Malignant Solid Neoplasm,
Location: Bethesda MD, Richmond VA, Charlottesville VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05327010

Phase2, Recruiting

Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06709404

Recruiting

TumorGlow Intraoperative Molecular Imaging (IMI)

for
Tumor, Solid
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT04723810

Phase1, Phase2, Recruiting

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

for
Metastatic Malignant Solid Neoplasm,
Location: Boston MA, Mineola NY, New York NY, Bethesda MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05687110

Phase1, Recruiting

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

for
Advanced Malignant Solid Neoplasm,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT04511039

Phase1, Recruiting

Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Upland CA, Lancaster CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 65+

Code: NCT06022965

Recruiting

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for
Metastatic Colorectal Carcinoma,
Location: The Bronx NY, Pittsburgh PA, Gainesville FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05803382

Phase1, Recruiting

Community-Based Physical Activity Intervention for Underserved Cancer Survivors

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06206863

Recruiting

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

for
Advanced Malignant Solid Neoplasm,
Location: New Haven CT, Trumbull CT, Bethesda MD, Pittsburgh PA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05691491

Phase1, Phase2, Recruiting

Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05772130

Recruiting

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

for
Advanced Malignant Solid Neoplasm, RAS Mutation, Lung Cancer,
Location: Nashville TN, Denver CO, Los Angeles CA
Sponsor: RasCal Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04678648

Phase1, Recruiting