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Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors

for
Ewing's Sarcoma, Soft Tissue Sarcoma, Hepatoblastoma,
Location: Chicago IL
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All

Age: 0 - 21

Code: NCT00179816

Phase1, Phase2, Recruiting

Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

for
Cancer
Location: New York NY, New Brunswick NJ, Philadelphia PA,
Sponsor: MBrace Therapeutics

Sex: All

Age: 18+

Code: NCT06014658

Phase1, Phase2, Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for
High Grade Epithelial Ovarian Cancer,
Location: Boston MA, Providence RI, Camden NJ, Doylestown PA,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT05579366

Phase1, Phase2, Recruiting

A Study of CRD3874-SI in People With Solid Tumors

for
Sarcoma, Merkel Cell Carcinoma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06021626

Phase1, Recruiting

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

for
Advanced Cancer, Metastatic Cancer
Location: Morristown NJ, Jacksonville FL, Chicago IL,
Sponsor: Qurient Co., Ltd.

Sex: All

Age: 18+

Code: NCT05394103

Phase1, Phase2, Recruiting

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A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

for
Ovarian Neoplasms, Endometrial Neoplasms,
Location: Mineola NY, New York NY, Columbus OH, Grand Rapids MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06400472

Phase1, Recruiting

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

for
Solid Tumours, Sarcoma, HNSCC, Non Small Cell Lung Cancer,
Location: Houston TX, Beverly Hills CA, Santa Monica CA
Sponsor: Epkin

Sex: All

Age: 18+

Code: NCT06789172

Phase1, Recruiting

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for
Advanced Cancer, Metastatic Cancer, Ovarian Cancer,
Location: Lake Success NY, Philadelphia PA, East Syracuse NY,
Sponsor: Artios Pharma Ltd

Sex: All

Age: 18+

Code: NCT04657068

Phase1, Phase2, Recruiting

Study of PF-07248144 in Advanced or Metastatic Solid Tumors

for
Locally Advanced or Metastatic ER+ HER2- Breast Cancer,
Location: New Haven CT, Edgewood KY, Louisville KY, Nashville TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT04606446

Phase2, Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 16+

Code: NCT05269381

Phase1, Phase2, Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

for
Advanced Endometrial Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05039801

Phase1, Recruiting

A Study of Injection HB0025 in Patients With Advanced Solid Tumors

for
Tumor, Subjects
Location: San Antonio TX
Sponsor: Huabo Biopharm Co., Ltd.

Sex: All

Age: 18+

Code: NCT04678908

Phase1, Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for
Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer,
Location: Boston MA, Providence RI, Montreal, Fairfax VA, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05797168

Phase1, Phase2, Recruiting

Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

for
Breast Cancer, Oligoprogressive, Head and Neck Cancer, Sarcoma,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06103669

Recruiting

Study Of Cold Cap Therapy For Prevention of Hairloss in Pediatric Patients Receiving Chemotherapy For Non-Malignant Indications and Solid Tumors

for
Alopecia
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 7+

Code: NCT04764357

Recruiting

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

for
Cancer, Cancer, Lung
Location: Lebanon NH, Philadelphia PA, Fairfax VA, Toronto,
Sponsor: Conjupro Biotherapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05948865

Phase1, Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04771520

Phase2, Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for
Colorectal Cancer, CRC, Pancreatic Ductal Adenocarcinoma, PDAC,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06445062

Phase1, Phase2, Recruiting

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

for
Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma,
Location: Fairfax VA, Pittsburgh PA, Canton OH, Columbus OH,
Sponsor: OncoNano Medicine, Inc.

Sex: All

Age: 18+

Code: NCT06022029

Phase1, Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Montreal, Fairfax VA, Toronto, Cleveland OH, Detroit MI,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05208762

Phase1, Recruiting