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Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

for
Advanced Solid Tumor Cancer
Location: Boston MA, Providence RI, New Haven CT, New York NY,
Sponsor: Calico Life Sciences LLC

Sex: All

Age: 18+

Code: NCT04777994

Phase1, Recruiting

A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors

for
Solid Tumor, Renal Cell Cancer Metastatic,
Location: Philadelphia PA, Dallas TX
Sponsor: Eutilex

Sex: All

Age: 18+

Code: NCT04903873

Phase1, Phase2, Recruiting

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

for
Advanced Solid Tumor, Diffuse Large B Cell Lymphoma,
Location: Boston MA, Philadelphia PA, Charlottesville VA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT04104776

Phase1, Phase2, Recruiting

Tempus Open Link for Individual Voices in Innovative Analytics Registry: Platform Protocol for Multimodal Real-World Evidence in Cancer

for
Cancer, Solid Tumor Cancer, Pediatric Acute Myeloid Leukemia,
Location: Chicago IL
Sponsor: Tempus AI

Sex: All

Age: 0+

Code: NCT07756034

Recruiting

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors, Colorectal Cancer,
Location: Fairfax VA, Denver CO, Sarasota FL, Nashville TN,
Sponsor: ArriVent BioPharma, Inc.

Sex: All

Age: 18+

Code: NCT07066657

Phase1, Recruiting

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A First-in-Human Study of CKD-703 in Advanced Solid Tumors and Non-Small Cell Lung Cancer

for
Advanced Solid Tumors, Non-Small Cell Lung Cancer
Location: Ohio City OH
Sponsor: Chong Kun Dang Pharmaceutical

Sex: All

Age: 19+

Code: NCT07439094

Phase1, Phase2, Recruiting

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

for
Small Cell Lung Cancer Extensive Stage, Brain Metastases,
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18+

Code: NCT07139990

Phase1, Recruiting

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

for
Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung Cancer,
Location: Montreal
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07468071

Phase1, Phase2, Recruiting

PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

for
Solid Tumor Malignancies, Metastatic Cancer, Breast Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06896162

Recruiting

A Study to Investigate ANS03 in Participants With Locally Advanced or Metastatic Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors Harboring a ROS1 or NTRK Alteration,
Location: New York NY
Sponsor: Avistone Biotechnology Co., Ltd.

Sex: All

Age: 18+

Code: NCT06716138

Phase1, Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer,
Location: Lake Success NY, Grand Rapids MI, Houston TX,
Sponsor: MacroGenics

Sex: All

Age: 18+

Code: NCT06242470

Phase1, Recruiting

Genomic Profiling in Cancer Patients

for
Solid Tumors, Hematologic Cancers
Location: Commack NY, Norwalk CT, Uniondale NY, Jamaica NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0+

Code: NCT01775072

Recruiting

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for
Malignant Solid Neoplasm
Location: Marshalltown IA, Ames IA, Boone IA, Fort Dodge IA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04871542

Recruiting

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

for
Locally Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 16+

Code: NCT04879121

Phase2, Recruiting

Studying TAK-243 in Patients With Advanced Cancer

for
Advanced Lymphoma, Advanced Malignant Solid Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06223542

Phase1, Recruiting

Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers

for
Metastatic Malignant Solid Neoplasm
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06606990

Phase1, Recruiting

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

for
Tumor, Solid, Pancreatic Cancer, Melanoma
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03454035

Phase1, Recruiting

Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers

for
Advanced Malignant Solid Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05691517

Phase1, Recruiting

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

for
Metastatic Malignant Solid Neoplasm,
Location: Boston MA, Deerfield Beach FL, Coral Gables FL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04585958

Phase1, Recruiting

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

for
Locally Advanced Malignant Solid Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03907475

Phase2, Recruiting