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Active & Responsive

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

for
Advanced Solid Cancers
Location: New York NY, Orlando FL, Denver CO
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07186842

Phase1, Phase2, Recruiting
Active & Responsive

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

for
Prostate Cancer Castration-resistant Prostate Cancer,
Location: East Brunswick NJ, Fairfax VA, Grand Rapids MI,
Sponsor: MBrace Therapeutics

Sex: All

Age: 18+

Code: NCT07145255

Phase1, Phase2, Recruiting
Active & Responsive

DBC-664 in Adult Patients With Solid Tumors

for
Malignant Germ Cell Tumor, Lung Adenocarcinoma,
Location: Lake Success NY, East Brunswick NJ, Grand Rapids MI,
Sponsor: Duboce Biopharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07705035

Phase1, Recruiting
Active & Responsive

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

for
Neuroblastoma, Rhabdomyosarcoma, Synovial Sarcoma,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 25

Code: NCT06625190

Phase1, Phase2, Recruiting
Active & Responsive

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for
Autoimmune Disease, Crohn Disease, Dermatomyositis,
Location: Boston MA, New Haven CT, Mineola NY, New York NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03816345

Phase1, Recruiting

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Active & Responsive

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

for
Rare Disorders, Undiagnosed Disorders,
Location: Sioux Falls SD
Sponsor: Sanford Health

Sex: All

Age: 0+

Code: NCT01793168

Recruiting
Active & Responsive

68Ga-PSMA-617 PET/CT for PSMA-expressing Tumor: a Pragmatic Study

for
Solid Cancers
Location: Sherbrooke
Sponsor: Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Sex: All

Age: 0+

Code: NCT05228106

Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for
Platinum-resistant Ovarian Cancer,
Location: Stony Brook NY, Greenville NC, Silver Spring MD,
Sponsor: Genelux Corporation

Sex: Female

Age: 18+

Code: NCT05281471

Phase3, Recruiting
Active & Responsive

Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial

for
Non-melanoma Skin Cancer, Carcinoma, Squamous Cell,
Location: Ottawa, Toronto, Edmonton, Vancouver
Sponsor: Women's College Hospital

Sex: All

Age: 18+

Code: NCT05955924

Phase3, Recruiting
New

B7-H3.CD28Z.CART in Solid Tumors

for
Pediatric Solid Tumor, Neuroblastoma
Location: Boston MA
Sponsor: Robbie Majzner

Sex: All

Age: 0 - 30

Code: NCT07358260

Phase1, Recruiting
New

First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors

for
Advanced Solid Tumors
Location: Fairfax VA, Grand Rapids MI, San Antonio TX, Duarte CA
Sponsor: VelaVigo Bio Inc

Sex: All

Age: 18+

Code: NCT07700160

Phase1, Phase2, Recruiting
New

A Study of DS3610a in Participants With Advanced Solid Tumor

for
Solid Tumors, Metastatic Solid Tumors
Location: Milwaukee WI
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT07159126

Phase1, Recruiting
New

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

for
Selected Advanced Solid Tumors, Colorectal Cancer (CRC),
Location: Glen Burnie MD
Sponsor: SK Life Science, Inc.

Sex: All

Age: 18+

Code: NCT07812805

Phase1, Recruiting
New

A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors
Location: Lake Success NY, Fairfax VA
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07730021

Phase1, Phase2, Recruiting
New

Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New York NY, Houston TX
Sponsor: OncoC4, Inc.

Sex: All

Age: 18+

Code: NCT07408258

Phase1, Recruiting

Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial

for
Rectal Cancer Stage II, Rectal Cancer Stage III,
Location: Anchorage AK
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 21+

Code: NCT06802172

Recruiting

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Philadelphia PA, Columbus OH,
Sponsor: Fate Therapeutics

Sex: All

Age: 18+

Code: NCT06241456

Phase1, Recruiting

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, New York NY, Washington D.C. DC, Durham NC,
Sponsor: OncoC4, Inc.

Sex: All

Age: 18+

Code: NCT06635785

Phase1, Phase2, Recruiting

A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)

for
Solid Tumors
Location: New Haven CT, Hackensack NJ, Los Angeles CA
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT05471856

Phase1, Recruiting