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Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

for
Hematologic Malignancy, Solid Tumor, Sickle Cell Disease,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 8+

Code: NCT06689800

Recruiting

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Philadelphia PA, Kissimmee FL, Gainesville FL,
Sponsor: OncoC4, Inc.

Sex: All

Age: 18+

Code: NCT06352359

Phase1, Recruiting

A Phase 1/2, Study of YL-15293 in Subjects With Advanced Solid Tumors With a KRAS G12C Mutation

for
Advanced Solid Tumor
Location: Houston TX
Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

Sex: All

Age: 18+

Code: NCT05119933

Phase1, Phase2, Recruiting

Anti-GD2 ADC M3554 in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, Houston TX
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18+

Code: NCT06641908

Phase1, Recruiting

AIMS Cancer Outcomes Study

for
Neoplasms, Neoplasm Malignant, Advanced Cancer,
Location: Seattle WA
Sponsor: Advanced Integrative Medical Science Institute

Sex: All

Age: 0+

Code: NCT04495790

Recruiting

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The Intersection of Oncology Care and Worker Well-Being

for
Solid Tumor
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: Male

Age: 21 - 70

Code: NCT05250284

Recruiting

A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

for
Solid Tumors
Location: Fairfax VA, Grand Rapids MI, Minneapolis MN, Houston TX,
Sponsor: Adcentrx Therapeutics

Sex: All

Age: 18+

Code: NCT06710379

Phase1, Recruiting

First in Human, Dose Escalation Study of AN4005

for
Advanced Solid Tumor, Advanced Lymphoma
Location: The Bronx NY, Hackensack NJ, Fairfax VA, Greenville SC
Sponsor: Adlai Nortye Biopharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT04999384

Phase1, Recruiting

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

for
Pediatric Brain Tumor, Pediatric Solid Tumor
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 6 - 21

Code: NCT05521984

Phase1, Recruiting

Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection

for
Solid Tumor
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT05585684

Recruiting

Safety Study of Camptothecin-20-O-Propionate Hydrate (CZ48)

for
Malignant Lymphoma of Extranodal and/or Solid Organ Site,
Location: San Antonio TX
Sponsor: Cao Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT02575638

Phase1, Recruiting

Dose Escalation and Expansion Study Evaluating ODC-IL2 in Adult Patients With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumors, Metastatic Solid Tumors
Location: Scottsdale AZ
Sponsor: Trutino Biosciences Inc.

Sex: All

Age: 18+

Code: NCT06770764

Phase1, Recruiting

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Boston MA, New Haven CT, New York NY, Tampa FL,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06917079

Phase1, Recruiting

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Boston MA, Westbury NY, New York NY, Washington D.C. DC,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06162221

Phase1, Phase2, Recruiting

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

for
Recurrent or Metastatic Solid Tumors
Location: Westbury NY, White Plains NY, New York NY, Fairfax VA,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06330064

Phase1, Phase2, Recruiting

Phase II Study of Asciminib for Second-line Treatment of Chronic Phase Chronic Myeloid Leukemia

for
Malignant Solid Tumors
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06629584

Phase2, Recruiting

Efficacy and Safety Study of OMTX705, Monotherapy and Anti-PD-1-combined, in Subjects With Advanced Solid Tumors.

for
Advanced Solid Tumor
Location: Boston MA
Sponsor: Oncomatryx Biopharma S.L.

Sex: All

Age: 18+

Code: NCT05547321

Phase1, Recruiting

Hyper-Personalized Medicine Using Patient Derived Xenografts (PDXovo) for Metastatic Solid Tumors

for
Kidney Neoplasm, Carcinoma, Renal Cell, Metastatic Solid Tumor
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT04602702

Recruiting

Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies

for
Solid Tumor
Location: Columbus OH, West Valley City UT
Sponsor: Jabez Bioscience, Inc

Sex: All

Age: 18+

Code: NCT06801002

Phase1, Recruiting

SNV1521 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New Haven CT, Philadelphia PA, Toronto, Nashville TN,
Sponsor: Synnovation Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06220864

Phase1, Recruiting