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A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

for
Advanced Solid Tumor, Metastatic Breast Cancer
Location: Lake Mary FL, Sarasota FL, Nashville TN, Houston TX
Sponsor: Edgewood Oncology Inc.

Sex: All

Age: 18+

Code: NCT04872166

Phase 1, Recruiting

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

for
Lung Cancer, Non-small Cell, Lung Cancer Metastatic,
Location: Weston FL, Canton OH, Cleveland OH, Detroit MI,
Sponsor: Krystal Biotech, Inc.

Sex: All

Age: 18+

Code: NCT06228326

Phase 1, Phase 2, Recruiting

ALG.APV-527 First-in-human Study

for
Solid Tumor
Location: Port Saint Lucie FL
Sponsor: Aptevo Therapeutics

Sex: All

Age: 18+

Code: NCT05934539

Phase 1, Phase 2, Recruiting

A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

for
Advanced Cancer, Solid Tumor, Metastatic Cancer
Location: Miami FL, Omaha NE, Duarte CA
Sponsor: Proviva Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06190886

Phase 1, Recruiting

Clinical Trial of PM54 in Advanced Solid Tumors Patients.

for
Advanced Solid Tumor
Location: San Antonio TX
Sponsor: PharmaMar

Sex: All

Age: 18+

Code: NCT05841563

Phase 1, Recruiting

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XTX301 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New Haven CT, Hackensack NJ, Pittsburgh PA, Canton OH,
Sponsor: Xilio Development, Inc.

Sex: All

Age: 18+

Code: NCT05684965

Phase 1, Phase 2, Recruiting

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, Ottawa, Fairfax VA, Toronto, San Antonio TX,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT06532565

Phase 1, Recruiting

CT-95 in Advanced Cancers Associated With Mesothelin Expression

for
Mesothelin-Expressing Tumors, Epithelial Ovarian Cancer,
Location: Hackensack NJ, Philadelphia PA, Grand Rapids MI,
Sponsor: Context Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06756035

Phase 1, Recruiting

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

for
Solid Tumor
Location: Fairfax VA, Myrtle Beach SC, Durham NC, Miami FL,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT06874335

Phase 1, Recruiting

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

for
Ovarian Cancer, Breast Cancer, Endometrial Cancer,
Location: Boston MA, Philadelphia PA, Falls Church VA, Buffalo NY,
Sponsor: NextCure, Inc.

Sex: All

Age: 18+

Code: NCT06774963

Phase 1, Recruiting

Cisplatin, Gemcitabine, Interferon Alfa, and Hyperthermia in Treating Patients With Advanced Cancer

for
Unspecified Adult Solid Tumor, Protocol Specific
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT00004063

Phase 1, Phase 2, Recruiting

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

for
Advanced HR+/HER2- Breast Cancer,
Location: Toronto, Atlanta GA, Nashville TN, San Antonio TX
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07288359

Phase 1, Phase 2, Recruiting

Brodalumab in the Treatment of Immune-Related Adverse Events

for
Breast Cancer, Esophageal Cancer, Kidney Cancer, Lung Cancer,
Location: New York NY
Sponsor: Brian Henick, MD

Sex: All

Age: 18+

Code: NCT06673329

Phase 1, Recruiting

Evaluation of AP-002 in Patients With Solid Tumors

for
Solid Tumor
Location: Saint Louis MO, Houston TX
Sponsor: Altum Pharmaceuticals INC

Sex: All

Age: 18+

Code: NCT04143789

Phase 1, Phase 2, Recruiting

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05118789

Phase 1, Phase 2, Recruiting

PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

for
Refractory Solid Tumors, Relapsed Solid Tumors,
Location: Boston MA, Philadelphia PA, Houston TX,
Sponsor: Theodore Laetsch

Sex: All

Age: 1 - 30

Code: NCT06721689

Phase 1, Phase 2, Recruiting

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

for
High-grade Glioma, Solid Tumor, Unspecified, Child
Location: Edison NJ, Miami FL, Little Rock AR
Sponsor: Laminar Pharmaceuticals

Sex: All

Age: 0 - 18

Code: NCT04299191

Phase 1, Phase 2, Recruiting

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New York NY, New Brunswick NJ, Orlando FL,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT05932862

Phase 1, Recruiting

Phase 1/2 Study of TU2218 Alone and in Combination With Checkpoint Inhibitors in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: San Antonio TX
Sponsor: TiumBio Co., Ltd.

Sex: All

Age: 18+

Code: NCT05204862

Phase 1, Phase 2, Recruiting

A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors

for
Solid Tumor
Location: Providence RI, Philadelphia PA, Fairfax VA,
Sponsor: Chugai Pharmaceutical

Sex: All

Age: 18+

Code: NCT05907980

Phase 1, Recruiting