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A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors
Location: Lake Success NY, Fairfax VA
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07730021

Phase 1, Phase 2, Recruiting

Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New York NY, Houston TX
Sponsor: OncoC4, Inc.

Sex: All

Age: 18+

Code: NCT07408258

Phase 1, Recruiting

Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic Solid Tumors
Location: Boston MA
Sponsor: Hanmi Pharmaceutical Company Limited

Sex: All

Age: 18+

Code: NCT06724016

Phase 1, Recruiting

Evaluate the Safety, Tolerability, and Preliminary Efficacy of EVM14 Alone and in Combination in Patients With Selected Solid Tumors

for
Selected Types of Solid Tumor
Location: New York NY, Fairfax VA, Houston TX
Sponsor: Everest Medicines (Beijing) Co., Ltd.

Sex: All

Age: 18+

Code: NCT07095868

Phase 1, Phase 2, Recruiting

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

for
Solid Tumor, Adult, Non-small Cell Lung Cancer, Melanoma
Location: New York NY, New Brunswick NJ, Morristown NJ,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 18+

Code: NCT04913285

Phase 1, Recruiting

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A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Durham NC, Cleveland OH,
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All

Age: 18+

Code: NCT06859762

Phase 1, Recruiting

A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors

for
Advanced-stage Solid Tumors
Location: Orlando FL, Irving TX
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07223125

Phase 1, Recruiting

First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies

for
Participants With Advanced Solid Tumor Malignancies
Location: Fairfax VA, Grand Rapids MI, Houston TX, San Antonio TX,
Sponsor: VelaVigo Bio Inc

Sex: All

Age: 18+

Code: NCT07136779

Phase 1, Phase 2, Recruiting

Phase 1/2 Study of Intravenous Injection of STX-003 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

for
Advanced Solid Tumor
Location: Nashville TN, Scottsdale AZ
Sponsor: Strand Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07751042

Phase 1, Phase 2, Recruiting

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New York NY, Fairfax VA, Huntersville NC,
Sponsor: Arvinas Inc.

Sex: All

Age: 18+

Code: NCT07749586

Phase 1, Phase 2, Recruiting

M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Toronto, San Antonio TX
Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All

Age: 18+

Code: NCT07166601

Phase 1, Recruiting

A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

for
Solid Tumor Malignancies
Location: Fairfax VA, Miami FL, Cincinnati OH, Grand Rapids MI,
Sponsor: Kumquat Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07207707

Phase 1, Recruiting

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

for
Advanced/Metastatic Solid Tumors, Bladder Cancer,
Location: Boston MA, Newton MA, New Haven CT, Trumbull CT,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07090499

Phase 1, Recruiting

BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

for
Solid Tumor Cancer, Locally Advanced, Metastatic Solid Tumors,
Location: Boston MA, New York NY, Houston TX, Austin TX,
Sponsor: Avenzo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07193511

Phase 1, Phase 2, Recruiting

TLN-372 in Advanced KRAS Mutant Solid Tumors

for
KRAS Mutant Solid Tumors
Location: Boston MA, New York NY, Toronto, Grand Rapids MI,
Sponsor: Treeline Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07204340

Phase 1, Recruiting

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor, Prostate Cancer,
Location: New York NY, Philadelphia PA, Lake Mary FL,
Sponsor: MOMA Therapeutics

Sex: All

Age: 18+

Code: NCT06545942

Phase 1, Recruiting

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

for
Advanced or Metastatic Solid Tumors,
Location: Houston TX, San Antonio TX, Scottsdale AZ
Sponsor: SHY Therapeutics

Sex: All

Age: 18+

Code: NCT07705334

Phase 1, Recruiting

Intratumoral N17350 in Advanced Solid Tumors

for
Neoplasms, Solid Tumor, Breast Neoplasms, Triple-Negative,
Location: Buffalo NY, Houston TX
Sponsor: Onchilles Pharma Inc

Sex: All

Age: 18+

Code: NCT07339176

Phase 1, Phase 2, Recruiting

Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

for
HER2 Expressing Solid Tumors
Location: New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: Vironexis Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT07192432

Phase 1, Phase 2, Recruiting

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Irving TX, Los Angeles CA
Sponsor: CStone Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06741644

Phase 1, Phase 2, Recruiting